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A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa.
Neumayer G, Torkelson JL, Li S, McCarthy K, Zhen HH, Vangipuram M, Mader MM, Gebeyehu G, Jaouni TM, Jacków-Malinowska J, Rami A, Hansen C, Guo Z, Gaddam S, Tate KM, Pappalardo A, Li L, Chow GM, Roy KR, Nguyen TM, Tanabe K, McGrath PS, Cramer A, Bruckner A, Bilousova G, Roop D, Tang JY, Christiano A, Steinmetz LM, Wernig M, Oro AE. Neumayer G, et al. Among authors: roy kr. Nat Commun. 2024 Jul 11;15(1):5834. doi: 10.1038/s41467-024-49400-z. Nat Commun. 2024. PMID: 38992003 Free PMC article.
Multiplexed precision genome editing with trackable genomic barcodes in yeast.
Roy KR, Smith JD, Vonesch SC, Lin G, Tu CS, Lederer AR, Chu A, Suresh S, Nguyen M, Horecka J, Tripathi A, Burnett WT, Morgan MA, Schulz J, Orsley KM, Wei W, Aiyar RS, Davis RW, Bankaitis VA, Haber JE, Salit ML, St Onge RP, Steinmetz LM. Roy KR, et al. Nat Biotechnol. 2018 Jul;36(6):512-520. doi: 10.1038/nbt.4137. Epub 2018 May 7. Nat Biotechnol. 2018. PMID: 29734294 Free PMC article.
Dissecting quantitative trait nucleotides by saturation genome editing.
Roy KR, Smith JD, Li S, Vonesch SC, Nguyen M, Burnett WT, Orsley KM, Lee CS, Haber JE, St Onge RP, Steinmetz LM. Roy KR, et al. bioRxiv [Preprint]. 2024 Feb 2:2024.02.02.577784. doi: 10.1101/2024.02.02.577784. bioRxiv. 2024. PMID: 38352467 Free PMC article. Preprint.
Genome-scale analysis of interactions between genetic perturbations and natural variation.
Hale JJ, Matsui T, Goldstein I, Mullis MN, Roy KR, Ville CN, Miller D, Wang C, Reynolds T, Steinmetz LM, Levy SF, Ehrenreich IM. Hale JJ, et al. Among authors: roy kr. bioRxiv [Preprint]. 2024 Jan 16:2023.05.06.539663. doi: 10.1101/2023.05.06.539663. bioRxiv. 2024. Update in: Nat Commun. 2024 May 18;15(1):4234. doi: 10.1038/s41467-024-48626-1 PMID: 38293072 Free PMC article. Updated. Preprint.
51 results