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A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa.
Neumayer G, Torkelson JL, Li S, McCarthy K, Zhen HH, Vangipuram M, Mader MM, Gebeyehu G, Jaouni TM, Jacków-Malinowska J, Rami A, Hansen C, Guo Z, Gaddam S, Tate KM, Pappalardo A, Li L, Chow GM, Roy KR, Nguyen TM, Tanabe K, McGrath PS, Cramer A, Bruckner A, Bilousova G, Roop D, Tang JY, Christiano A, Steinmetz LM, Wernig M, Oro AE. Neumayer G, et al. Among authors: wernig m. Nat Commun. 2024 Jul 11;15(1):5834. doi: 10.1038/s41467-024-49400-z. Nat Commun. 2024. PMID: 38992003 Free PMC article.
Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa.
Sebastiano V, Zhen HH, Haddad B, Bashkirova E, Melo SP, Wang P, Leung TL, Siprashvili Z, Tichy A, Li J, Ameen M, Hawkins J, Lee S, Li L, Schwertschkow A, Bauer G, Lisowski L, Kay MA, Kim SK, Lane AT, Wernig M, Oro AE. Sebastiano V, et al. Among authors: wernig m. Sci Transl Med. 2014 Nov 26;6(264):264ra163. doi: 10.1126/scitranslmed.3009540. Sci Transl Med. 2014. PMID: 25429056 Free PMC article.
Direct somatic lineage conversion.
Tanabe K, Haag D, Wernig M. Tanabe K, et al. Among authors: wernig m. Philos Trans R Soc Lond B Biol Sci. 2015 Oct 19;370(1680):20140368. doi: 10.1098/rstb.2014.0368. Philos Trans R Soc Lond B Biol Sci. 2015. PMID: 26416679 Free PMC article. Review.
TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment.
Li L, Wang Y, Torkelson JL, Shankar G, Pattison JM, Zhen HH, Fang F, Duren Z, Xin J, Gaddam S, Melo SP, Piekos SN, Li J, Liaw EJ, Chen L, Li R, Wernig M, Wong WH, Chang HY, Oro AE. Li L, et al. Among authors: wernig m. Cell Stem Cell. 2019 Feb 7;24(2):271-284.e8. doi: 10.1016/j.stem.2018.12.012. Epub 2019 Jan 24. Cell Stem Cell. 2019. PMID: 30686763 Free PMC article.
Is hypoimmunogenic stem cell therapy safe in times of pandemics?
Matheus F, Raveh T, Oro AE, Wernig M, Drukker M. Matheus F, et al. Among authors: wernig m. Stem Cell Reports. 2022 Apr 12;17(4):711-714. doi: 10.1016/j.stemcr.2022.02.014. Epub 2022 Mar 24. Stem Cell Reports. 2022. PMID: 35334219 Free PMC article. Review.
Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates.
Mall M, Kareta MS, Chanda S, Ahlenius H, Perotti N, Zhou B, Grieder SD, Ge X, Drake S, Euong Ang C, Walker BM, Vierbuchen T, Fuentes DR, Brennecke P, Nitta KR, Jolma A, Steinmetz LM, Taipale J, Südhof TC, Wernig M. Mall M, et al. Among authors: wernig m. Nature. 2017 Apr 13;544(7649):245-249. doi: 10.1038/nature21722. Epub 2017 Apr 5. Nature. 2017. PMID: 28379941 Free PMC article.
Transdifferentiation of human adult peripheral blood T cells into neurons.
Tanabe K, Ang CE, Chanda S, Olmos VH, Haag D, Levinson DF, Südhof TC, Wernig M. Tanabe K, et al. Among authors: wernig m. Proc Natl Acad Sci U S A. 2018 Jun 19;115(25):6470-6475. doi: 10.1073/pnas.1720273115. Epub 2018 Jun 4. Proc Natl Acad Sci U S A. 2018. PMID: 29866841 Free PMC article.
146 results