Trivedi A - Search Results

1

Food Effect and Pharmacokinetic Bridging of Avacopan in Caucasian and Japanese Healthy Participants.

Miao S, Bekker P, Armas D, Lor M, Hanada R, Okamura S, Umezawa Y, Trivedi A. Miao S, et al. Among authors: trivedi a. Clin Pharmacol Drug Dev. 2024 Sep;13(9):1011-1023. doi: 10.1002/cpdd.1436. Epub 2024 Jul 11. Clin Pharmacol Drug Dev. 2024. PMID: 38993035 Clinical Trial.

2

Pharmacokinetic Evaluation of the CYP3A4 and CYP2C9 Drug-Drug Interaction of Avacopan in 2 Open-Label Studies in Healthy Participants.

Miao S, Bekker P, Armas D, Lor M, Han Y, Webster K, Trivedi A. Miao S, et al. Among authors: trivedi a. Clin Pharmacol Drug Dev. 2024 May;13(5):517-533. doi: 10.1002/cpdd.1389. Epub 2024 Feb 29. Clin Pharmacol Drug Dev. 2024. PMID: 38423992

3

Effect of Mild or Moderate Hepatic Impairment on the Pharmacokinetics of Avacopan, a Small-Molecule Complement C5a Receptor Antagonist, for the Treatment of Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis.

Miao S, Suso P, Furst JA, Hudson MG, Trivedi A. Miao S, et al. Among authors: trivedi a. Clin Pharmacol Drug Dev. 2024 Sep;13(9):1000-1010. doi: 10.1002/cpdd.1444. Epub 2024 Jul 11. Clin Pharmacol Drug Dev. 2024. PMID: 38993026 Clinical Trial.

4

A Phase 1, Open-Label Study to Evaluate the Effect of Food and Concomitant Itraconazole Administration on the Pharmacokinetics of AMG 986 in Healthy Subjects.

Trivedi A, Mather O, Vega S, Hutton S, Hellawell J, Lee E. Trivedi A, et al. Clin Pharmacol Drug Dev. 2022 Jul;11(7):849-856. doi: 10.1002/cpdd.1074. Epub 2022 Mar 5. Clin Pharmacol Drug Dev. 2022. PMID: 35247290 Clinical Trial.

5

Pharmacokinetic Drug-Drug Interaction Study of Omecamtiv Mecarbil With Omeprazole, a Proton Pump Inhibitor, in Healthy Subjects.

Trivedi A, Sohn W, Jafarinasabian P, Zhang H, Terminello B, Flach S, Abbasi S, Dutta S, Lee E. Trivedi A, et al. Clin Pharmacol Drug Dev. 2022 Jan;11(1):129-133. doi: 10.1002/cpdd.997. Epub 2021 Jul 16. Clin Pharmacol Drug Dev. 2022. PMID: 34272833

6

Pharmacokinetic Drug-Drug Interaction Study of Omecamtiv Mecarbil With Amiodarone and Digoxin in Healthy Subjects.

Trivedi A, Sohn W, Hsu CP, Jafarinasabian P, Zhang H, Hutton S, Flach S, Abbasi S, Dutta S, Lee E. Trivedi A, et al. Clin Pharmacol Drug Dev. 2022 Mar;11(3):388-396. doi: 10.1002/cpdd.1028. Epub 2021 Oct 11. Clin Pharmacol Drug Dev. 2022. PMID: 34634185 Free PMC article.

7

Effect of Varying Degrees of Hepatic Impairment on the Pharmacokinetics of Omecamtiv Mecarbil.

Trivedi A, Oberoi RK, Mackowski M, Jafarinasabian P, Zhang H, Flach S, Hutton S, Abbasi S, Dutta S, Lee E. Trivedi A, et al. Clin Pharmacol Drug Dev. 2021 Dec;10(12):1442-1451. doi: 10.1002/cpdd.969. Epub 2021 Jun 9. Clin Pharmacol Drug Dev. 2021. PMID: 34107172

8

Pharmacokinetic Evaluation of the CYP3A4 and CYP2D6 Drug-Drug Interaction and CYP3A4 Induction Potential of Omecamtiv Mecarbil: Two Open-Label Studies in Healthy Subjects.

Trivedi A, Malik FI, Jafarinasabian P, Zhang H, Flach S, Abbasi S, Dutta S, Lee E. Trivedi A, et al. Clin Pharmacol Drug Dev. 2022 Feb;11(2):185-193. doi: 10.1002/cpdd.987. Epub 2021 Jun 19. Clin Pharmacol Drug Dev. 2022. PMID: 34145992

9

Pharmacokinetics, Tolerability, and Safety of Single and Multiple Omecamtiv Mecarbil Doses in Healthy Japanese and Caucasian Subjects.

Trivedi A, Malik FI, Mackowski M, Hutton S, Aoki M, Abbasi S, Dutta S, Lee E. Trivedi A, et al. Eur J Drug Metab Pharmacokinet. 2021 Nov;46(6):759-770. doi: 10.1007/s13318-021-00711-2. Epub 2021 Aug 20. Eur J Drug Metab Pharmacokinet. 2021. PMID: 34415561 Clinical Trial.

10

Effect of Omecamtiv Mecarbil on the Pharmacokinetics of Metformin, a Probe Substrate for MATE1/MATE2-K, in Healthy Subjects.

Trivedi A, Oberoi RK, Jafarinasabian P, Zhang H, Spring M, Flach S, Abbasi S, Dutta S, Lee E. Trivedi A, et al. Clin Drug Investig. 2021 Jul;41(7):647-652. doi: 10.1007/s40261-021-01051-4. Epub 2021 Jun 7. Clin Drug Investig. 2021. PMID: 34097256

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