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144 results

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Panitumumab plus 5-fluorouracil and folinic acid or 5-fluorouracil and folinic acid alone as maintenance therapy in RAS wild-type metastatic colorectal cancer (PanaMa, AIO KRK 0212): final efficacy analysis of a randomised, open-label, phase 2 trial.
Stahler A, Karthaus M, Fruehauf S, Graeven U, Müller L, Fischer von Weikersthal L, Caca K, Goekkurt E, Ballhausen A, Sommerhäuser G, Alig AHS, Held S, Jarosch A, Horst D, Reinacher-Schick A, Kasper S, Heinemann V, Stintzing S, Trarbach T, Modest DP. Stahler A, et al. Among authors: modest dp. EClinicalMedicine. 2024 Dec 16;79:103004. doi: 10.1016/j.eclinm.2024.103004. eCollection 2025 Jan. EClinicalMedicine. 2024. PMID: 39802302 Free PMC article.
Flow Cytometric Assessment of FcγRIIIa-V158F Polymorphisms and NK Cell Mediated ADCC Revealed Reduced NK Cell Functionality in Colorectal Cancer Patients.
Schiele P, Kolling S, Rosnev S, Junkuhn C, Walter AL, von Einem JC, Stintzing S, Schöning W, Sauer IM, Modest DP, Heinrich K, Weiss L, Heinemann V, Bullinger L, Frentsch M, Na IK. Schiele P, et al. Among authors: modest dp. Cells. 2024 Dec 31;14(1):32. doi: 10.3390/cells14010032. Cells. 2024. PMID: 39791733 Free PMC article.
Evaluation of circulating tumor DNA as a prognostic and predictive biomarker in BRAF V600E mutated colorectal cancer-results from the FIRE-4.5 study.
Klein-Scory S, Baraniskin A, Schmiegel W, Mika T, Schroers R, Held S, Heinrich K, Tougeron D, Modest DP, Schwaner I, Eucker J, Pihusch R, Stauch M, Kaiser F, Kahl C, Karthaus M, Müller C, Burkart C, Stintzing S, Heinemann V. Klein-Scory S, et al. Among authors: modest dp. Mol Oncol. 2024 Dec 4. doi: 10.1002/1878-0261.13778. Online ahead of print. Mol Oncol. 2024. PMID: 39630848 Free article.
Correction: Is interval chemotherapy safe and does it improve the outcome of patients with colorectal liver metastases undergoing multimodal two-stage hepatectomy? - A systematic literature review.
Raschzok N, Moosburner S, Blank M, Krenzien F, Lurje G, Schöning W, Sauer IM, Pratschke J, Modest DP, Kurreck A. Raschzok N, et al. Among authors: modest dp. BMC Cancer. 2024 Nov 11;24(1):1382. doi: 10.1186/s12885-024-13152-2. BMC Cancer. 2024. PMID: 39528976 Free PMC article. No abstract available.
Is interval chemotherapy safe and does it improve the outcome of patients with colorectal liver metastases undergoing multimodal two-stage hepatectomy? - A systematic literature review.
Raschzok N, Moosburner S, Blank M, Krenzien F, Lurje G, Schöning W, Sauer IM, Pratschke J, Modest DP, Kurreck A. Raschzok N, et al. Among authors: modest dp. BMC Cancer. 2024 Oct 10;24(1):1260. doi: 10.1186/s12885-024-13008-9. BMC Cancer. 2024. PMID: 39390396 Free PMC article.
Clinical prognosticators and targets in the immune microenvironment of intrahepatic cholangiocarcinoma.
Lozzi I, Arnold A, Barone M, Johnson JC, Sinn BV, Eschrich J, Gebert P, Wang R, Hu M, Feldbrügge L, Schirmeier A, Reutzel-Selke A, Malinka T, Krenzien F, Schöning W, Modest DP, Pratschke J, Sauer IM, Felsenstein M. Lozzi I, et al. Among authors: modest dp. Oncoimmunology. 2024 Oct 1;13(1):2406052. doi: 10.1080/2162402X.2024.2406052. eCollection 2024. Oncoimmunology. 2024. PMID: 39359389 Free PMC article.
Risk of bowel obstruction in patients with colon cancer responding to immunotherapy: an international case series.
Platt JR, Allotey J, Alouani E, Glasbey J, Intini R, Lonardi S, Mazzoli G, Militello AM, Modest DP, Palle J, Pietrantonio F, Riyad K, Samuel L, Schulze AV, Shiu KK, Taieb J, Tolan DJM, West NP, Westwood AC, Williams CJM, Seligmann JF. Platt JR, et al. Among authors: modest dp. ESMO Open. 2024 Sep;9(9):103698. doi: 10.1016/j.esmoop.2024.103698. Epub 2024 Sep 5. ESMO Open. 2024. PMID: 39241497 Free PMC article.
Impact of primary tumor sidedness and sex on prognosis and anti-epidermal growth factor receptor antibody efficacy in BRAF-mutant metastatic colorectal cancer: a pooled analysis of AIO studies FIRE-1, CIOX, FIRE-3, XELAVIRI, and VOLFI.
Alig AHS, Modest DP, Stintzing S, Heinrich K, Geissler M, Fischer von Weikersthal L, Decker T, Vehling-Kaiser U, Held S, Moosmann N, Stahler A, Tannapfel A, Giessen-Jung C, Jung A, Weiss L, Heinemann V. Alig AHS, et al. Among authors: modest dp. ESMO Open. 2024 Sep;9(9):103677. doi: 10.1016/j.esmoop.2024.103677. Epub 2024 Aug 21. ESMO Open. 2024. PMID: 39173562 Free PMC article.
Alternating gemcitabine plus nab-paclitaxel and gemcitabine alone versus continuous gemcitabine plus nab-paclitaxel after induction treatment of metastatic pancreatic cancer (ALPACA): a multicentre, randomised, open-label, phase 2 trial.
Dorman K, Boeck S, Caca K, Reichert M, Ettrich TJ, Oettle H, Waidmann O, Modest DP, Müller L, Michl P, Kanzler S, Pink D, Reinacher-Schick A, Geißler M, Pelz H, Kunzmann V, Held S, Schichtl T, Heinemann V, Kullmann F. Dorman K, et al. Among authors: modest dp. Lancet Gastroenterol Hepatol. 2024 Oct;9(10):935-943. doi: 10.1016/S2468-1253(24)00197-3. Epub 2024 Aug 16. Lancet Gastroenterol Hepatol. 2024. PMID: 39159648 Clinical Trial.
144 results