Botelho RJ - Search Results

1

Pressure sensing of lysosomes enables control of TFEB responses in macrophages.

Cai R, Scott O, Ye G, Le T, Saran E, Kwon W, Inpanathan S, Sayed BA, Botelho RJ, Saric A, Uderhardt S, Freeman SA. Cai R, et al. Among authors: botelho rj. Nat Cell Biol. 2024 Aug;26(8):1247-1260. doi: 10.1038/s41556-024-01459-y. Epub 2024 Jul 12. Nat Cell Biol. 2024. PMID: 38997458

2

The Phosphoinositide-Gated Lysosomal Ca(2+) Channel, TRPML1, Is Required for Phagosome Maturation.

Dayam RM, Saric A, Shilliday RE, Botelho RJ. Dayam RM, et al. Among authors: botelho rj. Traffic. 2015 Sep;16(9):1010-26. doi: 10.1111/tra.12303. Epub 2015 Jun 18. Traffic. 2015. PMID: 26010303 Free article.

3

mTOR controls lysosome tubulation and antigen presentation in macrophages and dendritic cells.

Saric A, Hipolito VE, Kay JG, Canton J, Antonescu CN, Botelho RJ. Saric A, et al. Among authors: botelho rj. Mol Biol Cell. 2016 Jan 15;27(2):321-33. doi: 10.1091/mbc.E15-05-0272. Epub 2015 Nov 18. Mol Biol Cell. 2016. PMID: 26582390 Free PMC article.

4

The Lysosome Signaling Platform: Adapting With the Times.

Inpanathan S, Botelho RJ. Inpanathan S, et al. Among authors: botelho rj. Front Cell Dev Biol. 2019 Jun 20;7:113. doi: 10.3389/fcell.2019.00113. eCollection 2019. Front Cell Dev Biol. 2019. PMID: 31281815 Free PMC article. Review.

5

Enhanced translation expands the endo-lysosome size and promotes antigen presentation during phagocyte activation.

Hipolito VEB, Diaz JA, Tandoc KV, Oertlin C, Ristau J, Chauhan N, Saric A, Mclaughlan S, Larsson O, Topisirovic I, Botelho RJ. Hipolito VEB, et al. Among authors: botelho rj. PLoS Biol. 2019 Dec 4;17(12):e3000535. doi: 10.1371/journal.pbio.3000535. eCollection 2019 Dec. PLoS Biol. 2019. PMID: 31800587 Free PMC article.

6

Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes.

Lancaster CE, Fountain A, Dayam RM, Somerville E, Sheth J, Jacobelli V, Somerville A, Terebiznik MR, Botelho RJ. Lancaster CE, et al. Among authors: botelho rj. J Cell Biol. 2021 Sep 6;220(9):e202005072. doi: 10.1083/jcb.202005072. Epub 2021 Jun 28. J Cell Biol. 2021. PMID: 34180943 Free PMC article.

7

Phagosome maturation in macrophages: Eat, digest, adapt, and repeat.

Fountain A, Inpanathan S, Alves P, Verdawala MB, Botelho RJ. Fountain A, et al. Among authors: botelho rj. Adv Biol Regul. 2021 Dec;82:100832. doi: 10.1016/j.jbior.2021.100832. Epub 2021 Oct 8. Adv Biol Regul. 2021. PMID: 34717137 Review.

8

Reactive oxygen species prevent lysosome coalescence during PIKfyve inhibition.

Saffi GT, Tang E, Mamand S, Inpanathan S, Fountain A, Salmena L, Botelho RJ. Saffi GT, et al. Among authors: botelho rj. PLoS One. 2021 Nov 23;16(11):e0259313. doi: 10.1371/journal.pone.0259313. eCollection 2021. PLoS One. 2021. PMID: 34813622 Free PMC article.

9

Arf1-PI4KIIIβ positive vesicles regulate PI(3)P signaling to facilitate lysosomal tubule fission.

Boutry M, DiGiovanni LF, Demers N, Fountain A, Mamand S, Botelho RJ, Kim PK. Boutry M, et al. Among authors: botelho rj. J Cell Biol. 2023 Sep 4;222(9):e202205128. doi: 10.1083/jcb.202205128. Epub 2023 Jun 8. J Cell Biol. 2023. PMID: 37289133 Free PMC article.

10

Salmonella actively modulates TFEB in murine macrophages in a growth-phase and time-dependent manner.

Inpanathan S, Ospina-Escobar E, Li VC, Adamji Z, Lackraj T, Cho YH, Porco N, Choy CH, McPhee JB, Botelho RJ. Inpanathan S, et al. Among authors: botelho rj. Microbiol Spectr. 2024 Jan 11;12(1):e0498122. doi: 10.1128/spectrum.04981-22. Epub 2023 Dec 5. Microbiol Spectr. 2024. PMID: 38051049 Free PMC article.

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