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Precise in vivo RNA base editing with a wobble-enhanced circular CLUSTER guide RNA.
Reautschnig P, Fruhner C, Wahn N, Wiegand CP, Kragness S, Yung JF, Hofacker DT, Fisk J, Eidelman M, Waffenschmidt N, Feige M, Pfeiffer LS, Schulz AE, Füll Y, Levanon EY, Mandel G, Stafforst T. Reautschnig P, et al. Among authors: fruhner c. Nat Biotechnol. 2024 Jul 12. doi: 10.1038/s41587-024-02313-0. Online ahead of print. Nat Biotechnol. 2024. PMID: 38997581
Profiling the interactome of oligonucleotide drugs by proximity biotinylation.
Hanswillemenke A, Hofacker DT, Sorgenfrei M, Fruhner C, Franz-Wachtel M, Schwarzer D, Maček B, Stafforst T. Hanswillemenke A, et al. Among authors: fruhner c. Nat Chem Biol. 2024 May;20(5):555-565. doi: 10.1038/s41589-023-01530-z. Epub 2024 Jan 17. Nat Chem Biol. 2024. PMID: 38233583 Free PMC article.
An improved SNAP-ADAR tool enables efficient RNA base editing to interfere with post-translational protein modification.
Kiran Kumar KD, Singh S, Schmelzle SM, Vogel P, Fruhner C, Hanswillemenke A, Brun A, Wettengel J, Füll Y, Funk L, Mast V, Botsch JJ, Reautschnig P, Li JB, Stafforst T. Kiran Kumar KD, et al. Among authors: fruhner c. Nat Commun. 2024 Aug 5;15(1):6615. doi: 10.1038/s41467-024-50395-w. Nat Commun. 2024. PMID: 39103360 Free PMC article.