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ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models.
Schmid S, Russell ZR, Yamashita AS, West ME, Parrish AG, Walker J, Rudoy D, Yan JZ, Quist DC, Gessesse BN, Alvinez N, Hill KD, Anderson LW, Cimino PJ, Kumasaka DK, Parchment RE, Holland EC, Szulzewsky F. Schmid S, et al. Among authors: cimino pj. Cell Rep. 2024 Oct 22;43(10):114829. doi: 10.1016/j.celrep.2024.114829. Epub 2024 Oct 3. Cell Rep. 2024. PMID: 39365700 Free PMC article.
HOXD12 defines an age-related aggressive subtype of oligodendroglioma.
Nuechterlein N, Cimino S, Shelbourn A, Ha V, Arora S, Rajan S, Shapiro LG, Holland EC, Aldape K, McGranahan T, Gilbert MR, Cimino PJ. Nuechterlein N, et al. Among authors: cimino pj. Acta Neuropathol. 2024 Sep 11;148(1):41. doi: 10.1007/s00401-024-02802-1. Acta Neuropathol. 2024. PMID: 39259414 Free PMC article.
Molecular classification to refine surgical and radiotherapeutic decision-making in meningioma.
Wang JZ, Patil V, Landry AP, Gui C, Ajisebutu A, Liu J, Saarela O, Pugh SL, Won M, Patel Z, Yakubov R, Kaloti R, Wilson C, Cohen-Gadol A, Zaazoue MA, Tabatabai G, Tatagiba M, Behling F, Almiron Bonnin DA, Holland EC, Kruser TJ, Barnholtz-Sloan JS, Sloan AE, Horbinski C, Chotai S, Chambless LB, Gao A, Rebchuk AD, Makarenko S, Yip S, Sahm F, Maas SLN, Tsang DS; International Consortium on Meningiomas (ICOM); Rogers CL, Aldape K, Nassiri F, Zadeh G. Wang JZ, et al. Nat Med. 2024 Nov;30(11):3173-3183. doi: 10.1038/s41591-024-03167-4. Epub 2024 Aug 21. Nat Med. 2024. PMID: 39169220 Free PMC article.
Papillary tumor of the pineal region: analysis of DNA methylation profiles and clinical outcomes in 76 cases.
Wu Z, Dazelle K, Abdullaev Z, Chung HJ, Dahiya S, Wood M, Lee H, Lucas CG, Mao Q, Robinson L, Fernandes I, McCord M, Pytel P, Conway KS, Yoda R, Eschbacher JM, Maher OM, Hasselblatt M, Mobley BC, Raisanen JM, Hatanpaa KJ, Byers J, Lehman NL, Cimino PJ, Pratt D, Quezado M, Aldape K. Wu Z, et al. Among authors: cimino pj. Acta Neuropathol Commun. 2024 Jul 16;12(1):117. doi: 10.1186/s40478-024-01781-4. Acta Neuropathol Commun. 2024. PMID: 39014393 Free PMC article.
Non-Motor Symptoms in Primary Familial Brain Calcification.
Bonato G, Cimino P, Pistonesi F, Salviati L, Bertolin C, Carecchio M. Bonato G, et al. Among authors: cimino p. J Clin Med. 2024 Jun 30;13(13):3873. doi: 10.3390/jcm13133873. J Clin Med. 2024. PMID: 38999439 Free PMC article.
Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome.
Thirimanne HN, Almiron-Bonnin D, Nuechterlein N, Arora S, Jensen M, Parada CA, Qiu C, Szulzewsky F, English CW, Chen WC, Sievers P, Nassiri F, Wang JZ, Klisch TJ, Aldape KD, Patel AJ, Cimino PJ, Zadeh G, Sahm F, Raleigh DR, Shendure J, Ferreira M, Holland EC. Thirimanne HN, et al. Among authors: cimino pj. Cell Genom. 2024 Jun 12;4(6):100566. doi: 10.1016/j.xgen.2024.100566. Epub 2024 May 23. Cell Genom. 2024. PMID: 38788713 Free PMC article.
Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model.
Lim S, Kwak M, Kang J, Cesaire M, Tang K, Robey RW, Frye WJE, Karim B, Butcher D, Lizak MJ, Dalmage M, Foster B, Nuechterlein N, Eberhart C, Cimino PJ, Gottesman MM, Jackson S. Lim S, et al. Among authors: cimino pj. Acta Neuropathol Commun. 2024 Apr 8;12(1):56. doi: 10.1186/s40478-024-01763-6. Acta Neuropathol Commun. 2024. PMID: 38589905 Free PMC article.
Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype.
Nuechterlein N, Shelbourn A, Szulzewsky F, Arora S, Casad M, Pattwell S, Merino-Galan L, Sulman E, Arowa S, Alvinez N, Jung M, Brown D, Tang K, Jackson S, Stoica S, Chittaboina P, Banasavadi-Siddegowda YK, Wirsching HG, Stella N, Shapiro L, Paddison P, Patel AP, Gilbert MR, Abdullaev Z, Aldape K, Pratt D, Holland EC, Cimino PJ. Nuechterlein N, et al. Among authors: cimino pj. Genes Dev. 2024 Apr 17;38(5-6):273-288. doi: 10.1101/gad.351350.123. Genes Dev. 2024. PMID: 38589034 Free PMC article.
ERK signaling promotes resistance to TRK kinase inhibition in NTRK fusion-driven glioma mouse models.
Schmid S, Russell ZR, Yamashita AS, West ME, Parrish AG, Walker J, Rudoy D, Yan JZ, Quist DC, Gessesse BN, Alvinez N, Cimino PJ, Kumasaka DK, Parchment RE, Holland EC, Szulzewsky F. Schmid S, et al. Among authors: cimino pj. bioRxiv [Preprint]. 2024 Mar 26:2024.03.13.584849. doi: 10.1101/2024.03.13.584849. bioRxiv. 2024. Update in: Cell Rep. 2024 Oct 22;43(10):114829. doi: 10.1016/j.celrep.2024.114829 PMID: 38558981 Free PMC article. Updated. Preprint.
169 results