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Page 1
Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation.
Lui H, Zhang J, Makinson SR, Cahill MK, Kelley KW, Huang HY, Shang Y, Oldham MC, Martens LH, Gao F, Coppola G, Sloan SA, Hsieh CL, Kim CC, Bigio EH, Weintraub S, Mesulam MM, Rademakers R, Mackenzie IR, Seeley WW, Karydas A, Miller BL, Borroni B, Ghidoni R, Farese RV Jr, Paz JT, Barres BA, Huang EJ. Lui H, et al. Among authors: huang hy, huang ej. Cell. 2016 May 5;165(4):921-35. doi: 10.1016/j.cell.2016.04.001. Epub 2016 Apr 21. Cell. 2016. PMID: 27114033 Free PMC article.
Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults.
Sorrells SF, Paredes MF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-Verdugo JM, Yang Z, Alvarez-Buylla A. Sorrells SF, et al. Among authors: huang ej. Nature. 2018 Mar 15;555(7696):377-381. doi: 10.1038/nature25975. Epub 2018 Mar 7. Nature. 2018. PMID: 29513649 Free PMC article.
Does Adult Neurogenesis Persist in the Human Hippocampus?
Paredes MF, Sorrells SF, Cebrian-Silla A, Sandoval K, Qi D, Kelley KW, James D, Mayer S, Chang J, Auguste KI, Chang EF, Gutierrez Martin AJ, Kriegstein AR, Mathern GW, Oldham MC, Huang EJ, Garcia-Verdugo JM, Yang Z, Alvarez-Buylla A. Paredes MF, et al. Among authors: huang ej. Cell Stem Cell. 2018 Dec 6;23(6):780-781. doi: 10.1016/j.stem.2018.11.006. Cell Stem Cell. 2018. PMID: 30526879 Free PMC article. No abstract available.
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.
Zhang J, Velmeshev D, Hashimoto K, Huang YH, Hofmann JW, Shi X, Chen J, Leidal AM, Dishart JG, Cahill MK, Kelley KW, Liddelow SA, Seeley WW, Miller BL, Walther TC, Farese RV Jr, Taylor JP, Ullian EM, Huang B, Debnath J, Wittmann T, Kriegstein AR, Huang EJ. Zhang J, et al. Among authors: huang yh, huang b, huang ej. Nature. 2020 Dec;588(7838):459-465. doi: 10.1038/s41586-020-2709-7. Epub 2020 Aug 31. Nature. 2020. PMID: 32866962 Free PMC article.
Positive Controls in Adults and Children Support That Very Few, If Any, New Neurons Are Born in the Adult Human Hippocampus.
Sorrells SF, Paredes MF, Zhang Z, Kang G, Pastor-Alonso O, Biagiotti S, Page CE, Sandoval K, Knox A, Connolly A, Huang EJ, Garcia-Verdugo JM, Oldham MC, Yang Z, Alvarez-Buylla A. Sorrells SF, et al. Among authors: huang ej. J Neurosci. 2021 Mar 24;41(12):2554-2565. doi: 10.1523/JNEUROSCI.0676-20.2020. J Neurosci. 2021. PMID: 33762407 Free PMC article. Review.
Nests of dividing neuroblasts sustain interneuron production for the developing human brain.
Paredes MF, Mora C, Flores-Ramirez Q, Cebrian-Silla A, Del Dosso A, Larimer P, Chen J, Kang G, Gonzalez Granero S, Garcia E, Chu J, Delgado R, Cotter JA, Tang V, Spatazza J, Obernier K, Ferrer Lozano J, Vento M, Scott J, Studholme C, Nowakowski TJ, Kriegstein AR, Oldham MC, Hasenstaub A, Garcia-Verdugo JM, Alvarez-Buylla A, Huang EJ. Paredes MF, et al. Among authors: huang ej. Science. 2022 Jan 28;375(6579):eabk2346. doi: 10.1126/science.abk2346. Epub 2022 Jan 28. Science. 2022. PMID: 35084970 Free PMC article.
Proinflammatory immune cells disrupt angiogenesis and promote germinal matrix hemorrhage in prenatal human brain.
Chen J, Crouch EE, Zawadzki ME, Jacobs KA, Mayo LN, Choi JJ, Lin PY, Shaikh S, Tsui J, Gonzalez-Granero S, Waller S, Kelekar A, Kang G, Valenzuela EJ, Birrueta JO, Diafos LN, Wedderburn-Pugh K, Di Marco B, Xia W, Han CZ, Coufal NG, Glass CK, Fancy SPJ, Alfonso J, Kriegstein AR, Oldham MC, Garcia-Verdugo JM, Kutys ML, Lehtinen MK, Combes AJ, Huang EJ. Chen J, et al. Among authors: huang ej. Nat Neurosci. 2024 Nov;27(11):2115-2129. doi: 10.1038/s41593-024-01769-2. Epub 2024 Sep 30. Nat Neurosci. 2024. PMID: 39349662 Free PMC article.
Evaluating and treating neurobehavioral symptoms in professional American football players: Lessons from a case series.
Gardner RC, Possin KL, Hess CP, Huang EJ, Grinberg LT, Nolan AL, Cohn-Sheehy BI, Ghosh PM, Lanata S, Merrilees J, Kramer JH, Berger MS, Miller BL, Yaffe K, Rabinovici GD. Gardner RC, et al. Among authors: huang ej. Neurol Clin Pract. 2015 Aug;5(4):285-295. doi: 10.1212/CPJ.0000000000000157. Neurol Clin Pract. 2015. PMID: 26336629 Free PMC article.
219 results