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Page 1
Deconstructing intratumoral heterogeneity through multiomic and multiscale analysis of serial sections.
Schupp PG, Shelton SJ, Brody DJ, Eliscu R, Johnson BE, Mazor T, Kelley KW, Potts MB, McDermott MW, Huang EJ, Lim DA, Pieper RO, Berger MS, Costello JF, Phillips JJ, Oldham MC. Schupp PG, et al. Among authors: mazor t. bioRxiv [Preprint]. 2024 Mar 18:2023.06.21.545365. doi: 10.1101/2023.06.21.545365. bioRxiv. 2024. Update in: Cancers (Basel). 2024 Jul 01;16(13):2429. doi: 10.3390/cancers16132429 PMID: 37645893 Free PMC article. Updated. Preprint.
Intratumoral Heterogeneity of the Epigenome.
Mazor T, Pankov A, Song JS, Costello JF. Mazor T, et al. Cancer Cell. 2016 Apr 11;29(4):440-451. doi: 10.1016/j.ccell.2016.03.009. Cancer Cell. 2016. PMID: 27070699 Free PMC article. Review.
Patient-derived cells from recurrent tumors that model the evolution of IDH-mutant glioma.
Jones LE, Hilz S, Grimmer MR, Mazor T, Najac C, Mukherjee J, McKinney A, Chow T, Pieper RO, Ronen SM, Chang SM, Phillips JJ, Costello JF. Jones LE, et al. Among authors: mazor t. Neurooncol Adv. 2020 Jul 16;2(1):vdaa088. doi: 10.1093/noajnl/vdaa088. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 32904945 Free PMC article.
DNA Methylation and Somatic Mutations Converge on the Cell Cycle and Define Similar Evolutionary Histories in Brain Tumors.
Mazor T, Pankov A, Johnson BE, Hong C, Hamilton EG, Bell RJA, Smirnov IV, Reis GF, Phillips JJ, Barnes MJ, Idbaih A, Alentorn A, Kloezeman JJ, Lamfers MLM, Bollen AW, Taylor BS, Molinaro AM, Olshen AB, Chang SM, Song JS, Costello JF. Mazor T, et al. Cancer Cell. 2015 Sep 14;28(3):307-317. doi: 10.1016/j.ccell.2015.07.012. Cancer Cell. 2015. PMID: 26373278 Free PMC article.
Mutant IDH1 Expression Drives TERT Promoter Reactivation as Part of the Cellular Transformation Process.
Ohba S, Mukherjee J, Johannessen TC, Mancini A, Chow TT, Wood M, Jones L, Mazor T, Marshall RE, Viswanath P, Walsh KM, Perry A, Bell RJ, Phillips JJ, Costello JF, Ronen SM, Pieper RO. Ohba S, et al. Among authors: mazor t. Cancer Res. 2016 Nov 15;76(22):6680-6689. doi: 10.1158/0008-5472.CAN-16-0696. Epub 2016 Oct 6. Cancer Res. 2016. PMID: 27758882 Free PMC article.
Probing the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in gliomas: A phase 2 study of everolimus for recurrent adult low-grade gliomas.
Wahl M, Chang SM, Phillips JJ, Molinaro AM, Costello JF, Mazor T, Alexandrescu S, Lupo JM, Nelson SJ, Berger M, Prados M, Taylor JW, Butowski N, Clarke JL, Haas-Kogan D. Wahl M, et al. Among authors: mazor t. Cancer. 2017 Dec 1;123(23):4631-4639. doi: 10.1002/cncr.30909. Epub 2017 Jul 31. Cancer. 2017. PMID: 28759109 Free PMC article. Clinical Trial.
Genomic analysis of the origins and evolution of multicentric diffuse lower-grade gliomas.
Hayes J, Yu Y, Jalbert LE, Mazor T, Jones LE, Wood MD, Walsh KM, Bengtsson H, Hong C, Oberndorfer S, Roetzer T, Smirnov IV, Clarke JL, Aghi MK, Chang SM, Nelson SJ, Woehrer A, Phillips JJ, Solomon DA, Costello JF. Hayes J, et al. Among authors: mazor t. Neuro Oncol. 2018 Apr 9;20(5):632-641. doi: 10.1093/neuonc/nox205. Neuro Oncol. 2018. PMID: 29077933 Free PMC article.
Temozolomide-induced hypermutation is associated with distant recurrence and reduced survival after high-grade transformation of low-grade IDH-mutant gliomas.
Yu Y, Villanueva-Meyer J, Grimmer MR, Hilz S, Solomon DA, Choi S, Wahl M, Mazor T, Hong C, Shai A, Phillips JJ, Wainer BH, McDermott M, Haas-Kogan D, Taylor JW, Butowski N, Clarke JL, Berger MS, Molinaro AM, Chang SM, Costello JF, Oberheim Bush NA. Yu Y, et al. Among authors: mazor t. Neuro Oncol. 2021 Nov 2;23(11):1872-1884. doi: 10.1093/neuonc/noab081. Neuro Oncol. 2021. PMID: 33823014 Free PMC article.
Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
Johnson BE, Mazor T, Hong C, Barnes M, Aihara K, McLean CY, Fouse SD, Yamamoto S, Ueda H, Tatsuno K, Asthana S, Jalbert LE, Nelson SJ, Bollen AW, Gustafson WC, Charron E, Weiss WA, Smirnov IV, Song JS, Olshen AB, Cha S, Zhao Y, Moore RA, Mungall AJ, Jones SJM, Hirst M, Marra MA, Saito N, Aburatani H, Mukasa A, Berger MS, Chang SM, Taylor BS, Costello JF. Johnson BE, et al. Among authors: mazor t. Science. 2014 Jan 10;343(6167):189-193. doi: 10.1126/science.1239947. Epub 2013 Dec 12. Science. 2014. PMID: 24336570 Free PMC article.
49 results