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A vector-free microfluidic platform for intracellular delivery.
Sharei A, Zoldan J, Adamo A, Sim WY, Cho N, Jackson E, Mao S, Schneider S, Han MJ, Lytton-Jean A, Basto PA, Jhunjhunwala S, Lee J, Heller DA, Kang JW, Hartoularos GC, Kim KS, Anderson DG, Langer R, Jensen KF. Sharei A, et al. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2082-7. doi: 10.1073/pnas.1218705110. Epub 2013 Jan 22. Proc Natl Acad Sci U S A. 2013. PMID: 23341631 Free PMC article.
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery.
Lee H, Lytton-Jean AK, Chen Y, Love KT, Park AI, Karagiannis ED, Sehgal A, Querbes W, Zurenko CS, Jayaraman M, Peng CG, Charisse K, Borodovsky A, Manoharan M, Donahoe JS, Truelove J, Nahrendorf M, Langer R, Anderson DG. Lee H, et al. Nat Nanotechnol. 2012 Jun 3;7(6):389-93. doi: 10.1038/nnano.2012.73. Nat Nanotechnol. 2012. PMID: 22659608 Free PMC article.
Ex vivo cytosolic delivery of functional macromolecules to immune cells.
Sharei A, Trifonova R, Jhunjhunwala S, Hartoularos GC, Eyerman AT, Lytton-Jean A, Angin M, Sharma S, Poceviciute R, Mao S, Heimann M, Liu S, Talkar T, Khan OF, Addo M, von Andrian UH, Anderson DG, Langer R, Lieberman J, Jensen KF. Sharei A, et al. PLoS One. 2015 Apr 13;10(4):e0118803. doi: 10.1371/journal.pone.0118803. eCollection 2015. PLoS One. 2015. PMID: 25875117 Free PMC article.
Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates.
Dong Y, Love KT, Dorkin JR, Sirirungruang S, Zhang Y, Chen D, Bogorad RL, Yin H, Chen Y, Vegas AJ, Alabi CA, Sahay G, Olejnik KT, Wang W, Schroeder A, Lytton-Jean AK, Siegwart DJ, Akinc A, Barnes C, Barros SA, Carioto M, Fitzgerald K, Hettinger J, Kumar V, Novobrantseva TI, Qin J, Querbes W, Koteliansky V, Langer R, Anderson DG. Dong Y, et al. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):3955-60. doi: 10.1073/pnas.1322937111. Epub 2014 Feb 10. Proc Natl Acad Sci U S A. 2014. PMID: 24516150 Free PMC article.
A novel family of biodegradable poly(ester amide) elastomers.
Cheng H, Hill PS, Siegwart DJ, Vacanti N, Lytton-Jean AK, Cho SW, Ye A, Langer R, Anderson DG. Cheng H, et al. Adv Mater. 2011 Mar 25;23(12):H95-100. doi: 10.1002/adma.201003482. Epub 2011 Mar 10. Adv Mater. 2011. PMID: 21394790 Free PMC article. No abstract available.
33 results