Searcey M - Search Results

1

Light-activated azobenzene peptide inhibitor of the PD-1/PD-L1 interaction.

Hayward D, Goddard ZR, Cominetti MMD, Searcey M, Beekman AM. Hayward D, et al. Among authors: searcey m. Chem Commun (Camb). 2024 Aug 1;60(63):8228-8231. doi: 10.1039/d4cc01249f. Chem Commun (Camb). 2024. PMID: 39007209 Free PMC article.

2

Identification of selective protein-protein interaction inhibitors using efficient in silico peptide-directed ligand design.

Beekman AM, Cominetti MMD, Walpole SJ, Prabhu S, O'Connell MA, Angulo J, Searcey M. Beekman AM, et al. Among authors: searcey m. Chem Sci. 2019 Mar 22;10(16):4502-4508. doi: 10.1039/c9sc00059c. eCollection 2019 Apr 28. Chem Sci. 2019. PMID: 31057779 Free PMC article.

3

Peptide directed phthalocyanine-gold nanoparticles for selective photodynamic therapy of EGFR overexpressing cancers.

Goddard ZR, Beekman AM, Cominetti MMD, O'Connell MA, Chambrier I, Cook MJ, Marín MJ, Russell DA, Searcey M. Goddard ZR, et al. Among authors: searcey m. RSC Med Chem. 2020 Nov 19;12(2):288-292. doi: 10.1039/d0md00284d. RSC Med Chem. 2020. PMID: 34041483 Free PMC article.

4

Borylation via iridium catalysed C-H activation: a new concise route to duocarmycin derivatives.

Cominetti MMD, Goddard ZR, Hood BR, Beekman AM, O'Connell MA, Searcey M. Cominetti MMD, et al. Among authors: searcey m. Org Biomol Chem. 2024 Jul 10;22(27):5603-5607. doi: 10.1039/d4ob00814f. Org Biomol Chem. 2024. PMID: 38904084 Free PMC article.

5

A Peptide-Duocarmycin Conjugate Targeting the Thomsen-Friedenreich Antigen Has Potent and Selective Antitumor Activity.

Cartwright OC, Beekman AM, Cominetti MMD, Russell DA, Searcey M. Cartwright OC, et al. Among authors: searcey m. Bioconjug Chem. 2020 Jul 15;31(7):1745-1749. doi: 10.1021/acs.bioconjchem.0c00282. Epub 2020 Jun 15. Bioconjug Chem. 2020. PMID: 32515945

6

A small molecule drug conjugate (SMDC) of DUPA and a duocarmycin built on the solid phase.

Beekman AM, Cominetti MMD, Cartwright OC, Boger DL, Searcey M. Beekman AM, et al. Among authors: searcey m. Medchemcomm. 2019 Nov 27;10(12):2170-2174. doi: 10.1039/c9md00279k. eCollection 2019 Dec 1. Medchemcomm. 2019. PMID: 32879717 Free PMC article.

7

Active targeting of gold nanoparticles as cancer therapeutics.

Goddard ZR , Marín MJ , Russell DA , Searcey M . Goddard ZR , et al. Among authors: searcey m. Chem Soc Rev. 2020 Dec 7;49(23):8774-8789. doi: 10.1039/d0cs01121e. Epub 2020 Oct 22. Chem Soc Rev. 2020. PMID: 33089858 Review.

8

Junctions in DNA: underexplored targets for therapeutic intervention.

Ivens E, Cominetti MMD, Searcey M. Ivens E, et al. Among authors: searcey m. Bioorg Med Chem. 2022 Sep 1;69:116897. doi: 10.1016/j.bmc.2022.116897. Epub 2022 Jun 24. Bioorg Med Chem. 2022. PMID: 35764032 Free article. Review.

9

Identification of a new p53/MDM2 inhibitor motif inspired by studies of chlorofusin.

Cominetti MMD, Goffin SA, Raffel E, Turner KD, Ramoutar JC, O'Connell MA, Howell LA, Searcey M. Cominetti MMD, et al. Among authors: searcey m. Bioorg Med Chem Lett. 2015 Nov 1;25(21):4878-4880. doi: 10.1016/j.bmcl.2015.06.014. Epub 2015 Jun 14. Bioorg Med Chem Lett. 2015. PMID: 26115576

10

Cytotoxicity of Pyrazine-Based Cyclometalated (C^N^pz^C)Au(III) Carbene Complexes: Impact of the Nature of the Ancillary Ligand on the Biological Properties.

Bertrand B, Fernandez-Cestau J, Angulo J, Cominetti MMD, Waller ZAE, Searcey M, O'Connell MA, Bochmann M. Bertrand B, et al. Among authors: searcey m. Inorg Chem. 2017 May 15;56(10):5728-5740. doi: 10.1021/acs.inorgchem.7b00339. Epub 2017 Apr 25. Inorg Chem. 2017. PMID: 28441013 Free PMC article.

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