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Page 1
Modulation of Ligand-Gated Glycine Receptors Via Functional Monoclonal Antibodies.
Simard JR, Michelsen K, Wang Y, Yang C, Youngblood B, Grubinska B, Taborn K, Gillie DJ, Cook K, Chung K, Long AM, Hall BE, Shaffer PL, Foti RS, Gingras J. Simard JR, et al. J Pharmacol Exp Ther. 2022 Oct;383(1):56-69. doi: 10.1124/jpet.121.001026. Epub 2022 Aug 4. J Pharmacol Exp Ther. 2022. PMID: 35926871
Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies.
Mock M, Jacobitz AW, Langmead CJ, Sudom A, Yoo D, Humphreys SC, Alday M, Alekseychyk L, Angell N, Bi V, Catterall H, Chen CC, Chou HT, Conner KP, Cook KD, Correia AR, Dykstra A, Ghimire-Rijal S, Graham K, Grandsard P, Huh J, Hui JO, Jain M, Jann V, Jia L, Johnstone S, Khanal N, Kolvenbach C, Narhi L, Padaki R, Pelegri-O'Day EM, Qi W, Razinkov V, Rice AJ, Smith R, Spahr C, Stevens J, Sun Y, Thomas VA, van Driesche S, Vernon R, Wagner V, Walker KW, Wei Y, Winters D, Yang M, Campuzano IDG. Mock M, et al. Among authors: cook kd. MAbs. 2023 Jan-Dec;15(1):2256745. doi: 10.1080/19420862.2023.2256745. MAbs. 2023. PMID: 37698932 Free PMC article.
Utility of physiologically based pharmacokinetic modeling to predict inter-antibody variability in monoclonal antibody pharmacokinetics in mice.
Liu S, Humphreys SC, Cook KD, Conner KP, Correia AR, Jacobitz AW, Yang M, Primack R, Soto M, Padaki R, Lubomirski M, Smith R, Mock M, Thomas VA. Liu S, et al. Among authors: cook kd. MAbs. 2023 Jan-Dec;15(1):2263926. doi: 10.1080/19420862.2023.2263926. Epub 2023 Oct 12. MAbs. 2023. PMID: 37824334 Free PMC article.
Cellular Neonatal Fc Receptor Recycling Efficiencies can Differentiate Target-Independent Clearance Mechanisms of Monoclonal Antibodies.
Bryniarski MA, Tuhin MTH, Acker TM, Wakefield DL, Sethaputra PG, Cook KD, Soto M, Ponce M, Primack R, Jagarapu A, LaGory EL, Conner KP. Bryniarski MA, et al. Among authors: cook kd. J Pharm Sci. 2024 Sep;113(9):2879-2894. doi: 10.1016/j.xphs.2024.06.013. Epub 2024 Jun 19. J Pharm Sci. 2024. PMID: 38906252 Free article.
Rapid depletion of "catch-and-release" anti-ASGR1 antibody in vivo.
Devanaboyina SC, Li P, LaGory EL, Poon-Andersen C, Cook KD, Soto M, Wang Z, Dang K, Uyeda C, Case RB, Thomas VA, Primack R, Ponce M, Di M, Ouyang B, Kaner J, Lam SK, Mostafavi M. Devanaboyina SC, et al. Among authors: cook kd. MAbs. 2024 Jan-Dec;16(1):2383013. doi: 10.1080/19420862.2024.2383013. Epub 2024 Jul 25. MAbs. 2024. PMID: 39051531 Free PMC article.
88 results