Ito Y - Search Results

1

Translational Pharmacokinetic-Toxicodynamic Model of Myelosuppression for Dose Optimization in Combination Chemotherapy of Capecitabine and Oxaliplatin from Rats to Humans.

Kobuchi S, Arimoto M, Ito Y. Kobuchi S, et al. Among authors: ito y. J Pharmacol Exp Ther. 2024 Aug 19;390(3):318-330. doi: 10.1124/jpet.124.002260. J Pharmacol Exp Ther. 2024. PMID: 39009467

2

Pharmacokinetic and toxicodynamic evaluation of oxaliplatin-induced neuropathy and hematological toxicity in rats.

Ito Y, Kobuchi S, Shimizu R, Katsuyama Y. Ito Y, et al. Cancer Chemother Pharmacol. 2018 Jan;81(1):155-161. doi: 10.1007/s00280-017-3485-4. Epub 2017 Nov 21. Cancer Chemother Pharmacol. 2018. PMID: 29164296

3

Assessment of pharmacokinetic variations of capecitabine after multiple administration in rats: a physiologically based pharmacokinetic model.

Sakai S, Kobuchi S, Ito Y, Sakaeda T. Sakai S, et al. Among authors: ito y. Cancer Chemother Pharmacol. 2020 May;85(5):869-880. doi: 10.1007/s00280-020-04057-5. Epub 2020 Apr 2. Cancer Chemother Pharmacol. 2020. PMID: 32240335

4

Pharmacokinetics of clomipramine, an antidepressant, in poloxamer 407-induced hyperlipidaemic model rats.

Kobuchi S, Fukushima K, Shibata M, Ito Y, Sugioka N, Takada K. Kobuchi S, et al. Among authors: ito y. J Pharm Pharmacol. 2011 Apr;63(4):515-23. doi: 10.1111/j.2042-7158.2010.01245.x. Epub 2011 Mar 1. J Pharm Pharmacol. 2011. PMID: 21401603

5

Pharmacokinetic/pharmacodynamic modeling of 5-fluorouracil by using a biomarker to predict tumor growth in a rat model of colorectal cancer.

Kobuchi S, Ito Y, Okada K, Imoto K, Kuwano S, Takada K. Kobuchi S, et al. Among authors: ito y. J Pharm Sci. 2013 Jun;102(6):2056-2067. doi: 10.1002/jps.23547. Epub 2013 Apr 16. J Pharm Sci. 2013. PMID: 23592368

6

Semi-physiological pharmacokinetic-pharmacodynamic modeling and simulation of 5-fluorouracil for the whole time course of alterations in leukocyte, neutrophil and lymphocyte counts in rats.

Kobuchi S, Ito Y, Hayakawa T, Kuwano S, Baba A, Shinohara K, Nishimura A, Shibata N, Takada K. Kobuchi S, et al. Among authors: ito y. Xenobiotica. 2014 Sep;44(9):804-18. doi: 10.3109/00498254.2014.900588. Epub 2014 Mar 20. Xenobiotica. 2014. PMID: 24650147

7

Semi-physiological pharmacokinetic-pharmacodynamic (PK-PD) modeling and simulation of 5-fluorouracil for thrombocytopenia in rats.

Kobuchi S, Ito Y, Hayakawa T, Nishimura A, Shibata N, Takada K, Sakaeda T. Kobuchi S, et al. Among authors: ito y. Xenobiotica. 2015 Jan;45(1):19-28. doi: 10.3109/00498254.2014.943335. Epub 2014 Jul 22. Xenobiotica. 2015. PMID: 25050790

8

Pharmacokinetic-pharmacodynamic (PK-PD) modeling and simulation of 5-fluorouracil for erythropenia in rats.

Kobuchi S, Ito Y, Hayakawa T, Nishimura A, Shibata N, Takada K, Sakaeda T. Kobuchi S, et al. Among authors: ito y. J Pharmacol Toxicol Methods. 2014 Sep-Oct;70(2):134-44. doi: 10.1016/j.vascn.2014.07.007. Epub 2014 Jul 26. J Pharmacol Toxicol Methods. 2014. PMID: 25072509

9

Population pharmacokinetic modelling and simulation of 5-fluorouracil incorporating a circadian rhythm in rats.

Kobuchi S, Ito Y, Nakano Y, Sakaeda T. Kobuchi S, et al. Among authors: ito y. Xenobiotica. 2016 Jul;46(7):597-604. doi: 10.3109/00498254.2015.1100767. Epub 2015 Oct 27. Xenobiotica. 2016. PMID: 26503235

10

A validated LC-MS/MS method for the determination of canagliflozin, a sodium-glucose co-transporter 2 (SGLT-2) inhibitor, in a lower volume of rat plasma: application to pharmacokinetic studies in rats.

Kobuchi S, Yano K, Ito Y, Sakaeda T. Kobuchi S, et al. Among authors: ito y. Biomed Chromatogr. 2016 Oct;30(10):1549-55. doi: 10.1002/bmc.3720. Epub 2016 Apr 13. Biomed Chromatogr. 2016. PMID: 26989857

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