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Page 1
Skeletal muscle p53-depletion uncovers a mechanism of fuel usage suppression that enables efficient energy conservation.
Lenihan-Geels G, Garcia Carrizo F, Leer M, Gohlke S, Oster M, Pöhle-Kronawitter S, Ott C, Chadt A, Reinisch IN, Galhuber M, Li C, Jonas W, Jähnert M, Klaus S, Al-Hasani H, Grune T, Schürmann A, Madl T, Prokesch A, Schupp M, Schulz TJ. Lenihan-Geels G, et al. Among authors: chadt a. J Cachexia Sarcopenia Muscle. 2024 Oct;15(5):1772-1784. doi: 10.1002/jcsm.13529. Epub 2024 Jul 15. J Cachexia Sarcopenia Muscle. 2024. PMID: 39010299 Free PMC article.
Inhibition of proline-rich tyrosine kinase 2 restores cardioprotection by remote ischaemic preconditioning in type 2 diabetes.
Erkens R, Duse DA, Brum A, Chadt A, Becher S, Siragusa M, Quast C, Müssig J, Roden M, Cortese-Krott M, Ibáñez B, Lammert E, Fleming I, Jung C, Al-Hasani H, Heusch G, Kelm M. Erkens R, et al. Among authors: chadt a. Br J Pharmacol. 2024 Nov;181(21):4174-4194. doi: 10.1111/bph.16483. Epub 2024 Jul 2. Br J Pharmacol. 2024. PMID: 38956895
Depletion of TBC1D4 Improves the Metabolic Exercise Response by Overcoming Genetically Induced Peripheral Insulin Resistance.
Springer C, Binsch C, Weide D, Toska L, Cremer AL, Backes H, Scheel AK, Espelage L, Kotzka J, Sill S, Kurowski A, Kim D, Karpinski S, Schnurr TM, Hansen T, Hartwig S, Lehr S, Cames S, Brüning JC, Lienhard M, Herwig R, Börno S, Timmermann B, Al-Hasani H, Chadt A. Springer C, et al. Among authors: chadt a. Diabetes. 2024 Jul 1;73(7):1058-1071. doi: 10.2337/db23-0463. Diabetes. 2024. PMID: 38608276
Impact of physical fitness and exercise training on subcutaneous adipose tissue beiging markers in humans with and without diabetes and a high-fat diet-fed mouse model.
Bódis K, Breuer S, Crepzia-Pevzner A, Zaharia OP, Schön M, Saatmann N, Altenhofen D, Springer C, Szendroedi J, Wagner R, Al-Hasani H, Roden M, Pesta D, Chadt A; GDS Group. Bódis K, et al. Among authors: chadt a. Diabetes Obes Metab. 2024 Jan;26(1):339-350. doi: 10.1111/dom.15322. Epub 2023 Oct 23. Diabetes Obes Metab. 2024. PMID: 37869933
Overexpressing high levels of human vaspin limits high fat diet-induced obesity and enhances energy expenditure in a transgenic mouse.
Rapöhn I, Elias I, Weiner J, Pujol A, Kehr S, Chadt A, Al-Hasani H, Burkhardt R, Klöting N, Stumvoll M, Bosch F, Kovacs P, Heiker JT, Breitfeld J. Rapöhn I, et al. Among authors: chadt a. Front Endocrinol (Lausanne). 2023 Apr 19;14:1146454. doi: 10.3389/fendo.2023.1146454. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37152954 Free PMC article.
Deletion of Tbc1d4/As160 abrogates cardiac glucose uptake and increases myocardial damage after ischemia/reperfusion.
Binsch C, Barbosa DM, Hansen-Dille G, Hubert M, Hodge SM, Kolasa M, Jeruschke K, Weiß J, Springer C, Gorressen S, Fischer JW, Lienhard M, Herwig R, Börno S, Timmermann B, Cremer AL, Backes H, Chadt A, Al-Hasani H. Binsch C, et al. Among authors: chadt a. Cardiovasc Diabetol. 2023 Jan 27;22(1):17. doi: 10.1186/s12933-023-01746-2. Cardiovasc Diabetol. 2023. PMID: 36707786 Free PMC article.
E96V Mutation in the Kdelr3 Gene Is Associated with Type 2 Diabetes Susceptibility in Obese NZO Mice.
Altenhofen D, Khuong JM, Kuhn T, Lebek S, Görigk S, Kaiser K, Binsch C, Griess K, Knebel B, Belgardt BF, Cames S, Eickelschulte S, Stermann T, Rasche A, Herwig R, Weiss J, Vogel H, Schürmann A, Chadt A, Al-Hasani H. Altenhofen D, et al. Among authors: chadt a. Int J Mol Sci. 2023 Jan 3;24(1):845. doi: 10.3390/ijms24010845. Int J Mol Sci. 2023. PMID: 36614300 Free PMC article.
59 results