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Page 1
Therapeutic avenues in bone repair: Harnessing an anabolic osteopeptide, PEPITEM, to boost bone growth and prevent bone loss.
Lewis JW, Frost K, Neag G, Wahid M, Finlay M, Northall EH, Abudu O, Kemble S, Davis ET, Powell E, Palmer C, Lu J, Rainger GE, Iqbal AJ, Chimen M, Mahmood A, Jones SW, Edwards JR, Naylor AJ, McGettrick HM. Lewis JW, et al. Among authors: rainger ge. Cell Rep Med. 2024 Aug 20;5(8):101657. doi: 10.1016/j.xcrm.2024.101657. Epub 2024 Jul 9. Cell Rep Med. 2024. PMID: 38986622 Free PMC article. No abstract available.
PEPITEM, its tripeptide pharmacophores and their peptidomimetic analogues regulate the inflammatory response through parenteral and topical dosing in models of peritonitis and psoriasis.
Saviano A, Apta B, Tull S, Pezhman L, Fatima A, Sevim M, Mete A, Chimen M, Schettino A, Marigliano N, McGettrick HM, Iqbal AJ, Maione F, Rainger GE. Saviano A, et al. Among authors: rainger ge. Pharmacol Res. 2025 Jan 22:107624. doi: 10.1016/j.phrs.2025.107624. Online ahead of print. Pharmacol Res. 2025. PMID: 39855372
Therapeutic avenues in bone repair: Harnessing an anabolic osteopeptide, PEPITEM, to boost bone growth and prevent bone loss.
Lewis JW, Frost K, Neag G, Wahid M, Finlay M, Northall EH, Abudu O, Kemble S, Davis ET, Powell E, Palmer C, Lu J, Rainger GE, Iqbal AJ, Chimen M, Mahmood A, Jones SW, Edwards JR, Naylor AJ, McGettrick HM. Lewis JW, et al. Among authors: rainger ge. Cell Rep Med. 2024 May 21;5(5):101574. doi: 10.1016/j.xcrm.2024.101574. Cell Rep Med. 2024. PMID: 38776873 Free PMC article.
S100A8/A9 drives the formation of procoagulant platelets through GPIbα.
Colicchia M, Schrottmaier WC, Perrella G, Reyat JS, Begum J, Slater A, Price J, Clark JC, Zhi Z, Simpson MJ, Bourne JH, Poulter NS, Khan AO, Nicolson PLR, Pugh M, Harrison P, Iqbal AJ, Rainger GE, Watson SP, Thomas MR, Mutch NJ, Assinger A, Rayes J. Colicchia M, et al. Among authors: rainger ge. Blood. 2022 Dec 15;140(24):2626-2643. doi: 10.1182/blood.2021014966. Blood. 2022. PMID: 36026606 Free PMC article.
Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science.
Evans PC, Rainger GE, Mason JC, Guzik TJ, Osto E, Stamataki Z, Neil D, Hoefer IE, Fragiadaki M, Waltenberger J, Weber C, Bochaton-Piallat ML, Bäck M. Evans PC, et al. Among authors: rainger ge. Cardiovasc Res. 2020 Dec 1;116(14):2177-2184. doi: 10.1093/cvr/cvaa230. Cardiovasc Res. 2020. PMID: 32750108 Free PMC article. Review.
Appropriation of GPIbα from platelet-derived extracellular vesicles supports monocyte recruitment in systemic inflammation.
Chimen M, Evryviadou A, Box CL, Harrison MJ, Hazeldine J, Dib LH, Kuravi SJ, Payne H, Price JMJ, Kavanagh D, Iqbal AJ, Lax S, Kalia N, Brill A, Thomas SG, Belli A, Crombie N, Adams RA, Evans SA, Deckmyn H, Lord JM, Harrison P, Watson SP, Nash GB, Rainger GE. Chimen M, et al. Among authors: rainger ge. Haematologica. 2020 May;105(5):1248-1261. doi: 10.3324/haematol.2018.215145. Epub 2019 Aug 29. Haematologica. 2020. PMID: 31467123 Free PMC article.
102 results