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Treponema pallidum genetic diversity and its implications for targeted vaccine development: A cross-sectional study of early syphilis cases in Southwestern Colombia.
Salazar JC, Vargas-Cely F, García-Luna JA, Ramirez LG, Bettin EB, Romero-Rosas N, Amórtegui MF, Silva S, Oviedo O, Vigil J, La Vake CJ, Galindo X, Ramirez JD, Martínez-Valencia AJ, Caimano MJ, Hennelly CM, Aghakhanian F, Moody MA, Seña AC, Parr JB, Hawley KL, López-Medina E, Radolf JD. Salazar JC, et al. Among authors: parr jb. PLoS One. 2024 Jul 19;19(7):e0307600. doi: 10.1371/journal.pone.0307600. eCollection 2024. PLoS One. 2024. PMID: 39028747 Free PMC article.
A novel CRISPR-based malaria diagnostic capable of Plasmodium detection, species differentiation, and drug-resistance genotyping.
Cunningham CH, Hennelly CM, Lin JT, Ubalee R, Boyce RM, Mulogo EM, Hathaway N, Thwai KL, Phanzu F, Kalonji A, Mwandagalirwa K, Tshefu A, Juliano JJ, Parr JB. Cunningham CH, et al. Among authors: parr jb. EBioMedicine. 2021 Jun;68:103415. doi: 10.1016/j.ebiom.2021.103415. Epub 2021 Jun 14. EBioMedicine. 2021. PMID: 34139428 Free PMC article.
Extracellular Loops of the Treponema pallidum FadL Orthologs TP0856 and TP0858 Elicit IgG Antibodies and IgG+-Specific B-Cells in the Rabbit Model of Experimental Syphilis.
Delgado KN, Montezuma-Rusca JM, Orbe IC, Caimano MJ, La Vake CJ, Luthra A, Hennelly CM, Nindo FN, Meyer JW, Jones LD, Parr JB, Salazar JC, Moody MA, Radolf JD, Hawley KL. Delgado KN, et al. Among authors: parr jb. mBio. 2022 Aug 30;13(4):e0163922. doi: 10.1128/mbio.01639-22. Epub 2022 Jul 12. mBio. 2022. PMID: 35862766 Free PMC article.
High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny.
Lieberman NAP, Armstrong TD, Chung B, Pfalmer D, Hennelly CM, Haynes A, Romeis E, Wang QQ, Zhang RL, Kou CX, Ciccarese G, Conte ID, Cusini M, Drago F, Nakayama SI, Lee K, Ohnishi M, Konda KA, Vargas SK, Eguiluz M, Caceres CF, Klausner JD, Mitja O, Rompalo A, Mulcahy F, Hook EW 3rd, Hoffman IF, Matoga MM, Zheng H, Yang B, Lopez-Medina E, Ramirez LG, Radolf JD, Hawley KL, Salazar JC, Lukehart SA, Seña AC, Parr JB, Giacani L, Greninger AL. Lieberman NAP, et al. Among authors: parr jb. Front Microbiol. 2022 Sep 20;13:1007056. doi: 10.3389/fmicb.2022.1007056. eCollection 2022. Front Microbiol. 2022. PMID: 36204625 Free PMC article.
Prevalence of yaws and syphilis in the Ashanti region of Ghana and occurrence of H. ducreyi, herpes simplex virus 1 and herpes simplex virus 2 in skin lesions associated with treponematoses.
Boaitey YA, Owusu-Ofori A, Anyogu A, Aghakhanian F, Arora N, Parr JB, Bosshard PP, Raheem S, Gerbault P. Boaitey YA, et al. Among authors: parr jb. PLoS One. 2024 May 22;19(5):e0295088. doi: 10.1371/journal.pone.0295088. eCollection 2024. PLoS One. 2024. PMID: 38776332 Free PMC article.
Clinical Presentation of Early Syphilis and Genomic Sequences of Treponema pallidum Strains in Patient Specimens and Isolates Obtained by Rabbit Inoculation.
Yang L, Zhang X, Chen W, Seña AC, Zheng H, Jiang Y, Zhao P, Chen R, Wang L, Ke W, Salazar JC, Parr JB, Tucker JD, Hawley KL, Caimano MJ, Hennelly CM, Aghakanian F, Bettin EB, Zhang F, Chen JS, Moody MA, Radolf JD, Yang B. Yang L, et al. Among authors: parr jb. J Infect Dis. 2024 Dec 16;230(6):e1322-e1333. doi: 10.1093/infdis/jiae322. J Infect Dis. 2024. PMID: 38884588 Free PMC article.
Clinical and genomic diversity of Treponema pallidum subspecies pallidum to inform vaccine research: an international, molecular epidemiology study.
Seña AC, Matoga MM, Yang L, Lopez-Medina E, Aghakhanian F, Chen JS, Bettin EB, Caimano MJ, Chen W, Garcia-Luna JA, Hennelly CM, Jere E, Jiang Y, Juliano JJ, Pospíšilová P, Ramirez L, Šmajs D, Tucker JD, Vargas Cely F, Zheng H, Hoffman IF, Yang B, Moody MA, Hawley KL, Salazar JC, Radolf JD, Parr JB. Seña AC, et al. Among authors: parr jb. Lancet Microbe. 2024 Sep;5(9):100871. doi: 10.1016/S2666-5247(24)00087-9. Epub 2024 Aug 22. Lancet Microbe. 2024. PMID: 39181152 Free PMC article.
102 results