Isacoff EY - Search Results

1

Development of covalent chemogenetic K_2P channel activators.

Deal PE, Lee H, Mondal A, Lolicato M, Mendonça PRF, Black H, Jang S, El-Hilali X, Bryant C, Isacoff EY, Renslo AR, Minor DL Jr. Deal PE, et al. Among authors: isacoff ey. Cell Chem Biol. 2024 Jul 18;31(7):1305-1323.e9. doi: 10.1016/j.chembiol.2024.06.006. Cell Chem Biol. 2024. PMID: 39029456

2

How does voltage open an ion channel?

Tombola F, Pathak MM, Isacoff EY. Tombola F, et al. Among authors: isacoff ey. Annu Rev Cell Dev Biol. 2006;22:23-52. doi: 10.1146/annurev.cellbio.21.020404.145837. Annu Rev Cell Dev Biol. 2006. PMID: 16704338 Review.

3

Electrochemical coupling in the voltage-dependent phosphatase Ci-VSP.

Kohout SC, Bell SC, Liu L, Xu Q, Minor DL Jr, Isacoff EY. Kohout SC, et al. Among authors: isacoff ey. Nat Chem Biol. 2010 May;6(5):369-75. doi: 10.1038/nchembio.349. Epub 2010 Apr 4. Nat Chem Biol. 2010. PMID: 20364128 Free PMC article.

4

Multiple C-terminal tail Ca(2+)/CaMs regulate Ca(V)1.2 function but do not mediate channel dimerization.

Kim EY, Rumpf CH, Van Petegem F, Arant RJ, Findeisen F, Cooley ES, Isacoff EY, Minor DL Jr. Kim EY, et al. Among authors: isacoff ey. EMBO J. 2010 Dec 1;29(23):3924-38. doi: 10.1038/emboj.2010.260. Epub 2010 Oct 15. EMBO J. 2010. PMID: 20953164 Free PMC article.

5

Optical probing of a dynamic membrane interaction that regulates the TREK1 channel.

Sandoz G, Bell SC, Isacoff EY. Sandoz G, et al. Among authors: isacoff ey. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2605-10. doi: 10.1073/pnas.1015788108. Epub 2011 Jan 24. Proc Natl Acad Sci U S A. 2011. PMID: 21262820 Free PMC article.

6

Calmodulin overexpression does not alter Cav1.2 function or oligomerization state.

Findeisen F, Tolia A, Arant R, Kim EY, Isacoff E, Minor DL Jr. Findeisen F, et al. Among authors: isacoff e. Channels (Austin). 2011 Jul-Aug;5(4):320-4. doi: 10.4161/chan.5.4.16821. Epub 2011 Jul 1. Channels (Austin). 2011. PMID: 21712653 Free PMC article.

7

A glutamate switch controls voltage-sensitive phosphatase function.

Liu L, Kohout SC, Xu Q, Müller S, Kimberlin CR, Isacoff EY, Minor DL Jr. Liu L, et al. Among authors: isacoff ey. Nat Struct Mol Biol. 2012 May 6;19(6):633-41. doi: 10.1038/nsmb.2289. Nat Struct Mol Biol. 2012. PMID: 22562138 Free PMC article.

8

Conduits of life's spark: a perspective on ion channel research since the birth of neuron.

Isacoff EY, Jan LY, Minor DL Jr. Isacoff EY, et al. Neuron. 2013 Oct 30;80(3):658-74. doi: 10.1016/j.neuron.2013.10.040. Neuron. 2013. PMID: 24183018 Free PMC article. Review.

9

Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels.

Levitz J, Royal P, Comoglio Y, Wdziekonski B, Schaub S, Clemens DM, Isacoff EY, Sandoz G. Levitz J, et al. Among authors: isacoff ey. Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):4194-9. doi: 10.1073/pnas.1522459113. Epub 2016 Mar 28. Proc Natl Acad Sci U S A. 2016. PMID: 27035963 Free PMC article.

10

Sequential Steps of CRAC Channel Activation.

Palty R, Fu Z, Isacoff EY. Palty R, et al. Among authors: isacoff ey. Cell Rep. 2017 May 30;19(9):1929-1939. doi: 10.1016/j.celrep.2017.05.025. Cell Rep. 2017. PMID: 28564609 Free PMC article.

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