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Fragile X Syndrome Patient-Derived Neurons Developing in the Mouse Brain Show FMR1-Dependent Phenotypes.
Krzisch MA, Wu H, Yuan B, Whitfield TW, Liu XS, Fu D, Garrett-Engele CM, Khalil AS, Lungjangwa T, Shih J, Chang AN, Warren S, Cacace A, Andrykovich KR, Rietjens RGJ, Wallace O, Sur M, Jain B, Jaenisch R. Krzisch MA, et al. Among authors: jaenisch r. Biol Psychiatry. 2023 Jan 1;93(1):71-81. doi: 10.1016/j.biopsych.2022.08.020. Epub 2022 Aug 28. Biol Psychiatry. 2023. PMID: 36372569
The A53T mutation in α-synuclein enhances pro-inflammatory activation in human microglia.
Krzisch M, Yuan B, Chen W, Osaki T, Fu D, Garrett-Engele C, Svoboda D, Andrykovich K, Sur M, Jaenisch R. Krzisch M, et al. Among authors: jaenisch r. bioRxiv [Preprint]. 2023 Aug 30:2023.08.29.555300. doi: 10.1101/2023.08.29.555300. bioRxiv. 2023. Update in: Biol Psychiatry. 2024 Jul 17:S0006-3223(24)01459-8. doi: 10.1016/j.biopsych.2024.07.011 PMID: 37693409 Free PMC article. Updated. Preprint.
Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes.
Wogram E, Sümpelmann F, Dong W, Rawat E, Fernández Maestre I, Fu D, Braswell B, Khalil A, Buescher JM, Mittler G, Borner GHH, Vlachos A, Tholen S, Schilling O, Bell GW, Rambold AS, Akhtar A, Schnell O, Beck J, Abu-Remaileh M, Prinz M, Jaenisch R. Wogram E, et al. Among authors: jaenisch r. Immunity. 2024 Sep 10;57(9):2216-2231.e11. doi: 10.1016/j.immuni.2024.07.019. Epub 2024 Aug 15. Immunity. 2024. PMID: 39151426
The nuclear receptor THRB facilitates differentiation of human PSCs into more mature hepatocytes.
Ma H, Zwaan E, Guo YE, Cejas P, Thiru P, van de Bunt M, Jeppesen JF, Syamala S, Dall'Agnese A, Abraham BJ, Fu D, Garrett-Engele C, Lee TI, Long HW, Griffith LG, Young RA, Jaenisch R. Ma H, et al. Among authors: jaenisch r. Cell Stem Cell. 2022 Nov 3;29(11):1611. doi: 10.1016/j.stem.2022.10.003. Cell Stem Cell. 2022. PMID: 36332573 Free PMC article. No abstract available.
Complex haploinsufficiency in pluripotent cells yields somatic cells with DNA methylation abnormalities and pluripotency induction defects.
Lasry R, Maoz N, Cheng AW, Yom Tov N, Kulenkampff E, Azagury M, Yang H, Ople C, Markoulaki S, Faddah DA, Makedonski K, Orzech D, Sabag O, Jaenisch R, Buganim Y. Lasry R, et al. Among authors: jaenisch r. Stem Cell Reports. 2023 Nov 14;18(11):2174-2189. doi: 10.1016/j.stemcr.2023.09.009. Epub 2023 Oct 12. Stem Cell Reports. 2023. PMID: 37832543 Free PMC article.
Tuning porosity of macroporous hydrogels enables rapid rates of stress relaxation and promotes cell expansion and migration.
Nerger BA, Kashyap K, Deveney BT, Lou J, Hanan BF, Liu Q, Khalil A, Lungjangwa T, Cheriyan M, Gupta A, Jaenisch R, Weitz DA, Mahadevan L, Mooney DJ. Nerger BA, et al. Among authors: jaenisch r. Proc Natl Acad Sci U S A. 2024 Nov 5;121(45):e2410806121. doi: 10.1073/pnas.2410806121. Epub 2024 Oct 28. Proc Natl Acad Sci U S A. 2024. PMID: 39467139
Abortive infection of bat fibroblasts with SARS-CoV-2.
Bisht P, Gallagher MD, Barrasa MI, Boucau J, Harding A, Déjosez M, Godoy-Parejo C, Bisher ME, de Nola G, Lytton-Jean AKR, Gehrke L, Zwaka TP, Jaenisch R. Bisht P, et al. Among authors: jaenisch r. Proc Natl Acad Sci U S A. 2024 Oct 22;121(43):e2406773121. doi: 10.1073/pnas.2406773121. Epub 2024 Oct 14. Proc Natl Acad Sci U S A. 2024. PMID: 39401365 Free PMC article.
650 results