Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

69 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Publication Date timeline is not available.
Page 1
Altered expression of Presenilin2 impacts endolysosomal homeostasis and synapse function in Alzheimer's disease-relevant brain circuits.
Perdok A, Van Acker ZP, Vrancx C, Sannerud R, Vorsters I, Verrengia A, Callaerts-Végh Z, Creemers E, Gutiérrez Fernández S, D'hauw B, Serneels L, Wierda K, Chávez-Gutiérrez L, Annaert W. Perdok A, et al. Among authors: serneels l. Nat Commun. 2024 Nov 29;15(1):10412. doi: 10.1038/s41467-024-54777-y. Nat Commun. 2024. PMID: 39613768 Free PMC article.
APOE from astrocytes restores Alzheimer's Aβ-pathology and DAM-like responses in APOE deficient microglia.
Preman P, Moechars D, Fertan E, Wolfs L, Serneels L, Shah D, Lamote J, Poovathingal S, Snellinx A, Mancuso R, Balusu S, Klenerman D, Arranz AM, Fiers M, De Strooper B. Preman P, et al. Among authors: serneels l. EMBO Mol Med. 2024 Dec;16(12):3113-3141. doi: 10.1038/s44321-024-00162-7. Epub 2024 Nov 11. EMBO Mol Med. 2024. PMID: 39528861 Free PMC article.
Alzheimer's disease-related presenilins are key to intestinal epithelial cell function and gut immune homoeostasis.
Erkert L, Gamez-Belmonte R, Kabisch M, Schödel L, Patankar JV, Gonzalez-Acera M, Mahapatro M, Bao LL, Plattner C, Kühl AA, Shen J, Serneels L, De Strooper B; TRR241 IBDome Consortium; Neurath MF, Wirtz S, Becker C. Erkert L, et al. Among authors: serneels l. Gut. 2024 Sep 9;73(10):1618-1631. doi: 10.1136/gutjnl-2023-331622. Gut. 2024. PMID: 38684238
Xenografted human microglia display diverse transcriptomic states in response to Alzheimer's disease-related amyloid-β pathology.
Mancuso R, Fattorelli N, Martinez-Muriana A, Davis E, Wolfs L, Van Den Daele J, Geric I, Premereur J, Polanco P, Bijnens B, Preman P, Serneels L, Poovathingal S, Balusu S, Verfaillie C, Fiers M, De Strooper B. Mancuso R, et al. Among authors: serneels l. Nat Neurosci. 2024 May;27(5):886-900. doi: 10.1038/s41593-024-01600-y. Epub 2024 Mar 27. Nat Neurosci. 2024. PMID: 38539015 Free PMC article.
The γ-secretase substrate proteome and its role in cell signaling regulation.
Hou P, Zielonka M, Serneels L, Martinez-Muriana A, Fattorelli N, Wolfs L, Poovathingal S, T'Syen D, Balusu S, Theys T, Fiers M, Mancuso R, Howden AJM, De Strooper B. Hou P, et al. Among authors: serneels l. Mol Cell. 2023 Nov 16;83(22):4106-4122.e10. doi: 10.1016/j.molcel.2023.10.029. Epub 2023 Nov 16. Mol Cell. 2023. PMID: 37977120 Free article.
MEG3 activates necroptosis in human neuron xenografts modeling Alzheimer's disease.
Balusu S, Horré K, Thrupp N, Craessaerts K, Snellinx A, Serneels L, T'Syen D, Chrysidou I, Arranz AM, Sierksma A, Simrén J, Karikari TK, Zetterberg H, Chen WT, Thal DR, Salta E, Fiers M, De Strooper B. Balusu S, et al. Among authors: serneels l. Science. 2023 Sep 15;381(6663):1176-1182. doi: 10.1126/science.abp9556. Epub 2023 Sep 14. Science. 2023. PMID: 37708272 Free PMC article.
69 results