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Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (ICECAP): study protocol for a multicenter, randomized, adaptive allocation clinical trial to identify the optimal duration of induced hypothermia for neuroprotection in comatose, adult survivors of after out-of-hospital cardiac arrest.
Meurer WJ, Schmitzberger FF, Yeatts S, Ramakrishnan V, Abella B, Aufderheide T, Barsan W, Benoit J, Berry S, Black J, Bozeman N, Broglio K, Brown J, Brown K, Carlozzi N, Caveney A, Cho SM, Chung-Esaki H, Clevenger R, Conwit R, Cooper R, Crudo V, Daya M, Harney D, Hsu C, Johnson NJ, Khan I, Khosla S, Kline P, Kratz A, Kudenchuk P, Lewis RJ, Madiyal C, Meyer S, Mosier J, Mouammar M, Neth M, O'Neil B, Paxton J, Perez S, Perman S, Sozener C, Speers M, Spiteri A, Stevenson V, Sunthankar K, Tonna J, Youngquist S, Geocadin R, Silbergleit R; ICECAP trial investigators. Meurer WJ, et al. Trials. 2024 Jul 23;25(1):502. doi: 10.1186/s13063-024-08280-w. Trials. 2024. PMID: 39044295 Free PMC article.
Is 'heads up' the way forward?
Paxton JH, O'Neil BJ. Paxton JH, et al. Resuscitation. 2021 Jan;158:270-272. doi: 10.1016/j.resuscitation.2020.11.009. Epub 2020 Nov 20. Resuscitation. 2021. PMID: 33227399 No abstract available.
When is PEA really ROSC?
Paxton JH, O'Neil BJ. Paxton JH, et al. Resuscitation. 2019 Sep;142:182-183. doi: 10.1016/j.resuscitation.2019.06.012. Epub 2019 Jun 21. Resuscitation. 2019. PMID: 31229475 No abstract available.
Early Convalescent Plasma for High-Risk Outpatients with Covid-19.
Korley FK, Durkalski-Mauldin V, Yeatts SD, Schulman K, Davenport RD, Dumont LJ, El Kassar N, Foster LD, Hah JM, Jaiswal S, Kaplan A, Lowell E, McDyer JF, Quinn J, Triulzi DJ, Van Huysen C, Stevenson VLW, Yadav K, Jones CW, Kea B, Burnett A, Reynolds JC, Greineder CF, Haas NL, Beiser DG, Silbergleit R, Barsan W, Callaway CW; SIREN-C3PO Investigators. Korley FK, et al. N Engl J Med. 2021 Nov 18;385(21):1951-1960. doi: 10.1056/NEJMoa2103784. Epub 2021 Aug 18. N Engl J Med. 2021. PMID: 34407339 Free PMC article. Clinical Trial.
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