Rago AJ - Search Results

1

Mining Medicinally Relevant Bioreduction Substrates Inspired by Ligand-Based Drug Design.

Rago AJ, Zoi I, Gartman JA, McDaniel KA, Jana N, Liu D, Bai WJ. Rago AJ, et al. J Med Chem. 2024 Aug 8;67(15):13174-13186. doi: 10.1021/acs.jmedchem.4c01129. Epub 2024 Jul 25. J Med Chem. 2024. PMID: 39051635

2

At the Speed of Light: The Systematic Implementation of Photoredox Cross-Coupling Reactions for Medicinal Chemistry Research.

Gesmundo NJ, Rago AJ, Young JM, Keess S, Wang Y. Gesmundo NJ, et al. Among authors: rago aj. J Org Chem. 2024 Nov 15;89(22):16070-16092. doi: 10.1021/acs.joc.3c02351. Epub 2024 Mar 5. J Org Chem. 2024. PMID: 38442262 Review.

3

Incorporating Synthetic Accessibility in Drug Design: Predicting Reaction Yields of Suzuki Cross-Couplings by Leveraging AbbVie's 15-Year Parallel Library Data Set.

Raghavan P, Rago AJ, Verma P, Hassan MM, Goshu GM, Dombrowski AW, Pandey A, Coley CW, Wang Y. Raghavan P, et al. Among authors: rago aj. J Am Chem Soc. 2024 Jun 5;146(22):15070-15084. doi: 10.1021/jacs.4c00098. Epub 2024 May 20. J Am Chem Soc. 2024. PMID: 38768950 Free PMC article.

4

Di(2-picolyl)amines as Modular and Robust Ligands for Nickel-Catalyzed C(sp²)-C(sp³) Cross-Electrophile Coupling.

Rago AJ, Vasilopoulos A, Dombrowski AW, Wang Y. Rago AJ, et al. Org Lett. 2022 Nov 25;24(46):8487-8492. doi: 10.1021/acs.orglett.2c03346. Epub 2022 Nov 15. Org Lett. 2022. PMID: 36377969

5

Direct β-Alkenylation of Ketones via Pd-Catalyzed Redox Cascade.

Wang C, Rago AJ, Dong G. Wang C, et al. Among authors: rago aj. Org Lett. 2019 May 3;21(9):3377-3381. doi: 10.1021/acs.orglett.9b01116. Epub 2019 Apr 16. Org Lett. 2019. PMID: 30990048

6

Unexpected ortho-Heck Reaction under the Catellani Conditions.

Rago AJ, Dong G. Rago AJ, et al. Org Lett. 2020 May 15;22(10):3770-3774. doi: 10.1021/acs.orglett.0c00952. Epub 2020 Apr 2. Org Lett. 2020. PMID: 32239958 Free PMC article.

7

Platinum-Catalyzed Desaturation of Lactams, Ketones, and Lactones.

Chen M, Rago AJ, Dong G. Chen M, et al. Among authors: rago aj. Angew Chem Int Ed Engl. 2018 Dec 3;57(49):16205-16209. doi: 10.1002/anie.201811197. Epub 2018 Nov 8. Angew Chem Int Ed Engl. 2018. PMID: 30325556

8

Synthesis of indoles, indolines, and carbazoles via palladium-catalyzed C─H activation.

Rago AJ, Dong G. Rago AJ, et al. Green Synth Catal. 2021 May;2(2):216-227. doi: 10.1016/j.gresc.2021.02.001. Epub 2021 Mar 4. Green Synth Catal. 2021. PMID: 36267892 Free PMC article.

9

Synthesis of C3,C4-Disubstituted Indoles via the Palladium/Norbornene-Catalyzed ortho-Amination/ipso-Heck Cyclization.

Rago AJ, Dong G. Rago AJ, et al. Org Lett. 2021 May 7;23(9):3755-3760. doi: 10.1021/acs.orglett.1c01165. Epub 2021 Apr 26. Org Lett. 2021. PMID: 33900777 Free PMC article.

10

A four-component reaction to access 3,3-disubstituted indolines via the palladium-norbornene-catalyzed ortho amination/ipso conjunctive coupling.

Rago AJ, Ye R, Liu X, Dong G. Rago AJ, et al. Chem Sci. 2023 Dec 14;15(4):1318-1323. doi: 10.1039/d3sc06409c. eCollection 2024 Jan 24. Chem Sci. 2023. PMID: 38274074 Free PMC article.

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