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Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations.
Wang Y, Le Y, Harris KL, Chen Y, Li X, Faske J, Wynne RA, Mittelstaedt RA, Cao X, Miranda-Colon J, Elkins L, Muskhelishvili L, Davis K, Mei N, Sun W, Robison TW, Heflich RH, Parsons BL. Wang Y, et al. Among authors: cao x. Mutat Res Genet Toxicol Environ Mutagen. 2024 Jul;897:503786. doi: 10.1016/j.mrgentox.2024.503786. Epub 2024 Jun 24. Mutat Res Genet Toxicol Environ Mutagen. 2024. PMID: 39054009
Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing.
Wang Y, Mittelstaedt RA, Wynne R, Chen Y, Cao X, Muskhelishvili L, Davis K, Robison TW, Sun W, Schmidt EK, Smith TH, Norgaard ZK, Valentine CC, Yaplee J, Williams LN, Salk JJ, Heflich RH. Wang Y, et al. Among authors: cao x. Environ Mol Mutagen. 2021 Jun;62(5):306-318. doi: 10.1002/em.22444. Epub 2021 Jun 14. Environ Mol Mutagen. 2021. PMID: 34050964 Free PMC article.
Report on stage III Pig-a mutation assays using benzo[a]pyrene.
Bhalli JA, Shaddock JG, Pearce MG, Dobrovolsky VN, Cao X, Heflich RH, Vohr HW. Bhalli JA, et al. Among authors: cao x. Environ Mol Mutagen. 2011 Dec;52(9):731-7. doi: 10.1002/em.20675. Epub 2011 Aug 29. Environ Mol Mutagen. 2011. PMID: 22052432
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