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Page 1
Descending facilitation from rostral ventromedial medulla mu opioid receptor-expressing neurons is necessary for maintenance of sensory and affective dimensions of chronic neuropathic pain.
Dogrul BN, Machado Kopruszinski C, Dolatyari Eslami M, Watanabe M, Luo S, Moreira de Souza LH, Vizin RL, Yue X, Palmiter RD, Navratilova E, Porreca F. Dogrul BN, et al. Among authors: navratilova e. Pain. 2025 Jan 1;166(1):153-159. doi: 10.1097/j.pain.0000000000003360. Epub 2024 Jul 26. Pain. 2025. PMID: 39058958
Antinociception depends on the presence of G protein gamma2-subunits in brain.
Varga EV, Hosohata K, Borys D, Navratilova E, Nylen A, Vanderah TW, Porreca F, Roeske WR, Yamamura HI. Varga EV, et al. Among authors: navratilova e. Eur J Pharmacol. 2005 Jan 31;508(1-3):93-8. doi: 10.1016/j.ejphar.2004.11.062. Epub 2005 Jan 12. Eur J Pharmacol. 2005. PMID: 15680258
Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists.
Yamamoto T, Nair P, Davis P, Ma SW, Navratilova E, Moye S, Tumati S, Lai J, Vanderah TW, Yamamura HI, Porreca F, Hruby VJ. Yamamoto T, et al. Among authors: navratilova e. J Med Chem. 2007 Jun 14;50(12):2779-86. doi: 10.1021/jm061369n. Epub 2007 May 22. J Med Chem. 2007. PMID: 17516639 Free PMC article.
A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists.
Yamamoto T, Nair P, Vagner J, Largent-Milnes T, Davis P, Ma SW, Navratilova E, Moye S, Tumati S, Lai J, Yamamura HI, Vanderah TW, Porreca F, Hruby VJ. Yamamoto T, et al. Among authors: navratilova e. J Med Chem. 2008 Mar 13;51(5):1369-76. doi: 10.1021/jm070332f. Epub 2008 Feb 12. J Med Chem. 2008. PMID: 18266313 Free PMC article.
The importance of micelle-bound states for the bioactivities of bifunctional peptide derivatives for delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists.
Yamamoto T, Nair P, Jacobsen NE, Davis P, Ma SW, Navratilova E, Moye S, Lai J, Yamamura HI, Vanderah TW, Porreca F, Hruby VJ. Yamamoto T, et al. Among authors: navratilova e. J Med Chem. 2008 Oct 23;51(20):6334-47. doi: 10.1021/jm800389v. Epub 2008 Sep 27. J Med Chem. 2008. PMID: 18821747 Free PMC article.
Novel bifunctional peptides as opioid agonists and NK-1 antagonists.
Nair P, Yamamoto T, Kulkarni V, Moye S, Navratilova E, Davis P, Largent T, Ma SW, Yamamura HI, Vanderah T, Lai J, Porreca F, Hruby VJ. Nair P, et al. Among authors: navratilova e. Adv Exp Med Biol. 2009;611:537-8. doi: 10.1007/978-0-387-73657-0_235. Adv Exp Med Biol. 2009. PMID: 19400302 Free PMC article. No abstract available.
Improving metabolic stability by glycosylation: bifunctional peptide derivatives that are opioid receptor agonists and neurokinin 1 receptor antagonists.
Yamamoto T, Nair P, Jacobsen NE, Vagner J, Kulkarni V, Davis P, Ma SW, Navratilova E, Yamamura HI, Vanderah TW, Porreca F, Lai J, Hruby VJ. Yamamoto T, et al. Among authors: navratilova e. J Med Chem. 2009 Aug 27;52(16):5164-75. doi: 10.1021/jm900473p. J Med Chem. 2009. PMID: 20560643 Free PMC article.
103 results