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Page 1
Structural basis for the inhibition of βFXIIa by garadacimab.
Drulyte I, Ghai R, Ow SY, Kapp EA, Quek AJ, Panousis C, Wilson MJ, Nash AD, Pelzing M. Drulyte I, et al. Among authors: panousis c. Structure. 2024 Oct 3;32(10):1705-1710.e3. doi: 10.1016/j.str.2024.07.001. Epub 2024 Jul 25. Structure. 2024. PMID: 39059382
DNA sequence specificity of mitoxantrone.
Panousis C, Phillips DR. Panousis C, et al. Nucleic Acids Res. 1994 Apr 25;22(8):1342-5. doi: 10.1093/nar/22.8.1342. Nucleic Acids Res. 1994. PMID: 8190623 Free PMC article.
A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk.
Larsson M, Rayzman V, Nolte MW, Nickel KF, Björkqvist J, Jämsä A, Hardy MP, Fries M, Schmidbauer S, Hedenqvist P, Broomé M, Pragst I, Dickneite G, Wilson MJ, Nash AD, Panousis C, Renné T. Larsson M, et al. Among authors: panousis c. Sci Transl Med. 2014 Feb 5;6(222):222ra17. doi: 10.1126/scitranslmed.3006804. Sci Transl Med. 2014. PMID: 24500405
CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors.
Panousis C, Dhagat U, Edwards KM, Rayzman V, Hardy MP, Braley H, Gauvreau GM, Hercus TR, Smith S, Sehmi R, McMillan L, Dottore M, McClure BJ, Fabri LJ, Vairo G, Lopez AF, Parker MW, Nash AD, Wilson NJ, Wilson MJ, Owczarek CM. Panousis C, et al. MAbs. 2016;8(3):436-53. doi: 10.1080/19420862.2015.1119352. Epub 2015 Dec 14. MAbs. 2016. PMID: 26651396 Free PMC article.
Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis.
Campbell IK, Leong D, Edwards KM, Rayzman V, Ng M, Goldberg GL, Wilson NJ, Scalzo-Inguanti K, Mackenzie-Kludas C, Lawlor KE, Wicks IP, Brown LE, Baz Morelli A, Panousis C, Wilson MJ, Nash AD, McKenzie BS, Andrews AE. Campbell IK, et al. Among authors: panousis c. J Immunol. 2016 Dec 1;197(11):4392-4402. doi: 10.4049/jimmunol.1600121. Epub 2016 Nov 2. J Immunol. 2016. PMID: 27807194
High-Throughput IgG Reformatting and Expression.
Chen CG, Sansome G, Wilson MJ, Panousis C. Chen CG, et al. Among authors: panousis c. Methods Mol Biol. 2018;1701:447-461. doi: 10.1007/978-1-4939-7447-4_25. Methods Mol Biol. 2018. PMID: 29116521
Antibody-mediated inhibition of FXIIa blocks downstream bradykinin generation.
Cao H, Biondo M, Lioe H, Busfield S, Rayzman V, Nieswandt B, Bork K, Harrison LC, Auyeung P, Farkas H, Csuka D, Pelzing M, Dower S, Wilson MJ, Nash A, Nolte MW, Panousis C. Cao H, et al. Among authors: panousis c. J Allergy Clin Immunol. 2018 Oct;142(4):1355-1358. doi: 10.1016/j.jaci.2018.06.014. Epub 2018 Jun 21. J Allergy Clin Immunol. 2018. PMID: 29936101 No abstract available.
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