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Conjugation of a 5-nitrofuran-2-oyl moiety to aminoalkylimidazoles produces non-toxic nitrofurans that are efficacious in vitro and in vivo against multidrug-resistant Mycobacterium tuberculosis.
Krasavin M, Lukin A, Vedekhina T, Manicheva O, Dogonadze M, Vinogradova T, Zabolotnykh N, Rogacheva E, Kraeva L, Yablonsky P. Krasavin M, et al. Eur J Med Chem. 2018 Sep 5;157:1115-1126. doi: 10.1016/j.ejmech.2018.08.068. Epub 2018 Aug 29. Eur J Med Chem. 2018. PMID: 30179748
Attachment of a 5-nitrofuroyl moiety to spirocyclic piperidines produces non-toxic nitrofurans that are efficacious in vitro against multidrug-resistant Mycobacterium tuberculosis.
Krasavin M, Lukin A, Vedekhina T, Manicheva O, Dogonadze M, Vinogradova T, Zabolotnykh N, Rogacheva E, Kraeva L, Sharoyko V, Tennikova TB, Dar'in D, Sokolovich E. Krasavin M, et al. Eur J Med Chem. 2019 Mar 15;166:125-135. doi: 10.1016/j.ejmech.2019.01.050. Epub 2019 Jan 23. Eur J Med Chem. 2019. PMID: 30703656
Mutually Isomeric 2- and 4-(3-nitro-1,2,4-triazol-1-yl)pyrimidines Inspired by an Antimycobacterial Screening Hit: Synthesis and Biological Activity against the ESKAPE Panel of Pathogens.
Chuprun S, Dar'in D, Rogacheva E, Kraeva L, Levin O, Manicheva O, Dogonadze M, Vinogradova T, Bakulina O, Krasavin M. Chuprun S, et al. Antibiotics (Basel). 2020 Oct 1;9(10):666. doi: 10.3390/antibiotics9100666. Antibiotics (Basel). 2020. PMID: 33019787 Free PMC article.
Enhancement of the Local CD8+ T-Cellular Immune Response to Mycobacterium tuberculosis in BCG-Primed Mice after Intranasal Administration of Influenza Vector Vaccine Carrying TB10.4 and HspX Antigens.
Vasilyev K, Shurygina AP, Zabolotnykh N, Sergeeva M, Romanovskaya-Romanko E, Pulkina A, Buzitskaya J, Dogonadze MZ, Vinogradova TI, Stukova MA. Vasilyev K, et al. Among authors: dogonadze mz. Vaccines (Basel). 2021 Nov 3;9(11):1273. doi: 10.3390/vaccines9111273. Vaccines (Basel). 2021. PMID: 34835204 Free PMC article.
30 results