Machlus K - Search Results

1

The Use of Clot Strength as a Predictor of Thrombosis in Peripheral Artery Disease.

Suarez Ferreira S, Agrawal A, Lee I, Rodriguez A, Cieri I, Young E, Patel S, Ghandour S, Morena L, Hagos F, Grobman B, Machlus K, Roy T, Dua A. Suarez Ferreira S, et al. Among authors: machlus k. Ann Vasc Surg. 2024 Dec;109:273-283. doi: 10.1016/j.avsg.2024.06.041. Epub 2024 Jul 26. Ann Vasc Surg. 2024. PMID: 39069123

2

The impact of sex on platelet responses to aspirin in patients with peripheral artery disease.

Suarez Ferreira SP, Hall RP, Morrow K, Patel S, Lee I, Hagos F, Zacharias N, Machlus K, Dua A. Suarez Ferreira SP, et al. Among authors: machlus k. Am J Hematol. 2024 Apr;99 Suppl 1(Suppl 1):S6-S12. doi: 10.1002/ajh.27258. Epub 2024 Feb 23. Am J Hematol. 2024. PMID: 38400527

3

The Impact of Sex on Antiplatelet and Anticoagulant Thromboprophylaxis in Patients With Peripheral Artery Disease Post-revascularization.

Suarez S, Agrawal A, Patel S, Grobman B, Ghandour S, Morena L, Rodriguez A, Machlus K, Roy T, Eagleton M, Dua A. Suarez S, et al. Among authors: machlus k. Ann Surg. 2024 Sep 1;280(3):463-472. doi: 10.1097/SLA.0000000000006375. Epub 2024 Jun 11. Ann Surg. 2024. PMID: 38860382

4

The many faces of the megakaryocytes and their biological implications.

Guo K, Machlus KR, Camacho V. Guo K, et al. Among authors: machlus kr. Curr Opin Hematol. 2024 Jan 1;31(1):1-5. doi: 10.1097/MOH.0000000000000793. Epub 2023 Nov 1. Curr Opin Hematol. 2024. PMID: 37910197 Free PMC article. Review.

5

Evidence for a cytoplasmic proplatelet promoting factor that triggers platelet production.

Italiano JE Jr, Machlus KR. Italiano JE Jr, et al. Among authors: machlus kr. Haematologica. 2024 Jul 1;109(7):2341-2345. doi: 10.3324/haematol.2023.284755. Haematologica. 2024. PMID: 38426280 Free PMC article. No abstract available.

6

SARS-CoV-2 infection modifies the transcriptome of the megakaryocytes in the bone marrow.

Allaeys I, Lemaire G, Leclercq M, Lacasse E, Fleury M, Dubuc I, Gudimard L, Puhm F, Tilburg J, Stone A, Machlus KR, Droit A, Flamand L, Boilard E. Allaeys I, et al. Among authors: machlus kr. Blood Adv. 2024 Jun 11;8(11):2777-2789. doi: 10.1182/bloodadvances.2023012367. Blood Adv. 2024. PMID: 38522092 Free PMC article.

7

CEBPA repression by MECOM blocks differentiation to drive aggressive leukemias.

Fleming TJ, Antoszewski M, Lambo S, Gundry MC, Piussi R, Wahlster L, Shah S, Reed FE, Dong KD, Paulo JA, Gygi SP, Mimoso C, Goldman SR, Adelman K, Perry JA, Pikman Y, Stegmaier K, Barrachina MN, Machlus KR, Hovestadt V, Arruda A, Minden MD, Voit RA, Sankaran VG. Fleming TJ, et al. Among authors: machlus kr. bioRxiv [Preprint]. 2024 Dec 30:2024.12.30.630680. doi: 10.1101/2024.12.30.630680. bioRxiv. 2024. PMID: 39803492 Free PMC article. Preprint.

8

Inhibition of RhoA-mediated secretory autophagy in megakaryocytes mitigates myelofibrosis in mice.

Becker IC, Barrachina MN, Lykins J, Camacho V, Stone AP, Chua BA, Signer RAJ, Machlus KR, Whiteheart SW, Roweth HG, Italiano JE. Becker IC, et al. Among authors: machlus kr. bioRxiv [Preprint]. 2024 Dec 5:2024.12.04.626665. doi: 10.1101/2024.12.04.626665. bioRxiv. 2024. PMID: 39677616 Free PMC article. Preprint.

9

Efficient megakaryopoiesis and platelet production require phospholipid remodeling and PUFA uptake through CD36.

Barrachina MN, Pernes G, Becker IC, Allaeys I, Hirsch TI, Groeneveld DJ, Khan AO, Freire D, Guo K, Carminita E, Morgan PK, Collins TJC, Mellett NA, Wei Z, Almazni I, Italiano JE, Luyendyk J, Meikle PJ, Puder M, Morgan NV, Boilard E, Murphy AJ, Machlus KR. Barrachina MN, et al. Among authors: machlus kr. Nat Cardiovasc Res. 2023 Aug;2(8):746-763. doi: 10.1038/s44161-023-00305-y. Epub 2023 Jul 17. Nat Cardiovasc Res. 2023. PMID: 39195958

10

Targeting cargo to an unconventional secretory system within megakaryocytes allows the release of transgenic proteins from platelets.

Asquith NL, Becker IC, Scimone MT, Boccia T, Camacho V, Barrachina MN, Guo S, Freire D, Machlus K, Schulman S, Flaumenhaft R, Italiano JE. Asquith NL, et al. Among authors: machlus k. J Thromb Haemost. 2024 Nov;22(11):3235-3248. doi: 10.1016/j.jtha.2024.07.021. Epub 2024 Aug 8. J Thromb Haemost. 2024. PMID: 39122192

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