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Synergistic drug interactions of the histone deacetylase inhibitor givinostat (ITF2357) in CRLF2-rearranged pediatric B-cell precursor acute lymphoblastic leukemia identified by high-throughput drug screening.
Oikonomou A, Watrin T, Valsecchi L, Scharov K, Savino AM, Schliehe-Diecks J, Bardini M, Fazio G, Bresolin S, Biondi A, Borkhardt A, Bhatia S, Cazzaniga G, Palmi C. Oikonomou A, et al. Among authors: bhatia s. Heliyon. 2024 Jul 3;10(13):e34033. doi: 10.1016/j.heliyon.2024.e34033. eCollection 2024 Jul 15. Heliyon. 2024. PMID: 39071567 Free PMC article.
GEMMs addressing Pax5 loss-of-function in childhood pB-ALL.
Auer F, Ingenhag D, Bhatia S, Enczmann J, Cobaleda C, Sanchez-Garcia I, Borkhardt A, Hauer J. Auer F, et al. Among authors: bhatia s. Eur J Med Genet. 2016 Mar;59(3):166-72. doi: 10.1016/j.ejmg.2015.11.009. Epub 2015 Nov 26. Eur J Med Genet. 2016. PMID: 26626503 Review.
Mouse models for pre-clinical drug testing in leukemia.
Bhatia S, Daschkey S, Lang F, Borkhardt A, Hauer J. Bhatia S, et al. Expert Opin Drug Discov. 2016 Nov;11(11):1081-1091. doi: 10.1080/17460441.2016.1229297. Epub 2016 Sep 9. Expert Opin Drug Discov. 2016. PMID: 27562952 Review.
Discovery of the First-in-Class Dual Histone Deacetylase-Proteasome Inhibitor.
Bhatia S, Krieger V, Groll M, Osko JD, Reßing N, Ahlert H, Borkhardt A, Kurz T, Christianson DW, Hauer J, Hansen FK. Bhatia S, et al. J Med Chem. 2018 Nov 21;61(22):10299-10309. doi: 10.1021/acs.jmedchem.8b01487. Epub 2018 Nov 8. J Med Chem. 2018. PMID: 30365892 Free PMC article.
Hydroxamic Acids Immobilized on Resins (HAIRs): Synthesis of Dual-Targeting HDAC Inhibitors and HDAC Degraders (PROTACs).
Sinatra L, Bandolik JJ, Roatsch M, Sönnichsen M, Schoeder CT, Hamacher A, Schöler A, Borkhardt A, Meiler J, Bhatia S, Kassack MU, Hansen FK. Sinatra L, et al. Among authors: bhatia s. Angew Chem Int Ed Engl. 2020 Dec 7;59(50):22494-22499. doi: 10.1002/anie.202006725. Epub 2020 Oct 9. Angew Chem Int Ed Engl. 2020. PMID: 32780485 Free PMC article.
3,541 results