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A phase 1, randomized, double-blind, placebo-controlled, dose escalation study to evaluate the safety, tolerability, pharmacokinetics and immunogenicity of SHR-1905, a long-acting anti-thymic stromal lymphopoietin antibody, in healthy subjects.
Fei Y, Li N, Qian W, Fan Y, Shen Y, Wang Q, McLendon K, Shen K. Fei Y, et al. Among authors: shen y, shen k. Front Pharmacol. 2024 Jul 15;15:1400696. doi: 10.3389/fphar.2024.1400696. eCollection 2024. Front Pharmacol. 2024. PMID: 39076593 Free PMC article.
Safety, pharmacokinetics and pharmacodynamics of HRS-7535, a novel oral small molecule glucagon-like peptide-1 receptor agonist, in healthy participants: A phase 1, randomized, double-blind, placebo-controlled, single- and multiple-ascending dose, and food effect trial.
Wu J, Zhou R, Zhang Q, Zhang Q, Qin H, Ye Z, Xu Y, Feng S, Shu C, Shen Y, Fan Y, Wang Q, Du Y, Hu W. Wu J, et al. Among authors: shen y. Diabetes Obes Metab. 2024 Mar;26(3):901-910. doi: 10.1111/dom.15383. Epub 2023 Dec 15. Diabetes Obes Metab. 2024. PMID: 38100147 Clinical Trial.
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