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Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy.
Bumpers QA, Pipal RW, Benz-Weeden AM, Brewster JT 2nd, Cook A, Crooks AL, Cruz C, Dwulet NC, Gaudino JJ, Golec D, Harrison JA, Hartley DP, Hassanien SH, Hicken EJ, Kahn D, Laird ER, Lemieux C, Lewandowski N, McCown J, McDonald MG, McNulty O, Mou TC, Nguyen P, Oko L, Opie LP, Otten J, Peck SC, Polites VC, Randall SD, Rosen RZ, Savechenkov P, Simpson H, Singh A, Sparks D, Wickersham K, Wollenberg L, Wong CE, Wong J, Wu WI, Elsayed MSA, Hinklin RJ, Tang TP. Bumpers QA, et al. Among authors: harrison ja. J Med Chem. 2024 Aug 22;67(16):14466-14477. doi: 10.1021/acs.jmedchem.4c01232. Epub 2024 Aug 1. J Med Chem. 2024. PMID: 39088797
A peptide antagonist of the TLR4-MD2 interaction.
Slivka PF, Shridhar M, Lee GI, Sammond DW, Hutchinson MR, Martinko AJ, Buchanan MM, Sholar PW, Kearney JJ, Harrison JA, Watkins LR, Yin H. Slivka PF, et al. Among authors: harrison ja. Chembiochem. 2009 Mar 2;10(4):645-9. doi: 10.1002/cbic.200800769. Chembiochem. 2009. PMID: 19184989 Free PMC article.
PEGylation of interleukin-10 for the mitigation of enhanced pain states.
Soderquist RG, Milligan ED, Harrison JA, Chavez RA, Johnson KW, Watkins LR, Mahoney MJ. Soderquist RG, et al. Among authors: harrison ja. J Biomed Mater Res A. 2010 Jun 1;93(3):1169-79. doi: 10.1002/jbm.a.32611. J Biomed Mater Res A. 2010. PMID: 19768789 Free PMC article.
183 results