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A phase I trial of LHC165 single agent and in combination with spartalizumab in patients with advanced solid malignancies.
Curigliano G, Jimenez MM, Shimizu T, Keam B, Meric-Bernstam F, Rutten A, Glaspy J, Schuler PJ, Parikh NS, Ising M, Hassounah N, Wu J, Leyk M, Chen X, Burks H, Chaudhury A, Otero J, Cabanas EG. Curigliano G, et al. Among authors: leyk m. ESMO Open. 2024 Aug;9(8):103643. doi: 10.1016/j.esmoop.2024.103643. Epub 2024 Jul 31. ESMO Open. 2024. PMID: 39088985 Free PMC article. Clinical Trial.
A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis.
Kappos L, Radue EW, O'Connor P, Polman C, Hohlfeld R, Calabresi P, Selmaj K, Agoropoulou C, Leyk M, Zhang-Auberson L, Burtin P; FREEDOMS Study Group. Kappos L, et al. Among authors: leyk m. N Engl J Med. 2010 Feb 4;362(5):387-401. doi: 10.1056/NEJMoa0909494. Epub 2010 Jan 20. N Engl J Med. 2010. PMID: 20089952 Free article. Clinical Trial.
Quality control of DL,CO instruments in global clinical trials.
Jensen R, Leyk M, Crapo R, Muchmore D, Berclaz PY. Jensen R, et al. Among authors: leyk m. Eur Respir J. 2009 Apr;33(4):828-34. doi: 10.1183/09031936.00091208. Epub 2009 Jan 7. Eur Respir J. 2009. PMID: 19129284 Free article.
Estrogen regulation of the cytochrome P450 3A subfamily in humans.
Williams ET, Leyk M, Wrighton SA, Davies PJ, Loose DS, Shipley GL, Strobel HW. Williams ET, et al. Among authors: leyk m. J Pharmacol Exp Ther. 2004 Nov;311(2):728-35. doi: 10.1124/jpet.104.068908. Epub 2004 Jul 28. J Pharmacol Exp Ther. 2004. PMID: 15282264 Clinical Trial.