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Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduction.
Wood GK, Sargent BF, Ahmad ZU, Tharmaratnam K, Dunai C, Egbe FN, Martin NH, Facer B, Pendered SL, Rogers HC, Hübel C, van Wamelen DJ, Bethlehem RAI, Giunchiglia V, Hellyer PJ, Trender W, Kalsi G, Needham E, Easton A, Jackson TA, Cunningham C, Upthegrove R, Pollak TA, Hotopf M, Solomon T, Pett SL, Shaw PJ, Wood N, Harrison NA, Miller KL, Jezzard P, Williams G, Duff EP, Williams S, Zelaya F, Smith SM, Keller S, Broome M, Kingston N, Husain M, Vincent A, Bradley J, Chinnery P, Menon DK, Aggleton JP, Nicholson TR, Taylor JP, David AS, Carson A, Bullmore E, Breen G, Hampshire A; COVID-CNS Consortium; Michael BD, Paddick SM, Leek EC. Wood GK, et al. Nat Med. 2024 Sep 23. doi: 10.1038/s41591-024-03309-8. Online ahead of print. Nat Med. 2024. PMID: 39312956
Evaluating the effectiveness of simvastatin in slowing the progression of disability in secondary progressive multiple sclerosis (MS-STAT2): protocol for a multicentre, randomised controlled, double-blind, phase 3 clinical trial in the UK.
Blackstone J, Williams T, Nicholas JM, Bordea E, De Angelis F, Bianchi A, Calvi A, Doshi A, John N, Apap Mangion S, Wade C, Merry R, Barton G, Lyle D, Jarman E, Mahad D, Shehu A, Arun T, McDonnell G, Geraldes R, Craner M, Hillier C, Ganesalingam J, Fisniku L, Hobart J, Spilker C, Robertson N, Kalra S, Pluchino S, Harikrishnan S, Mattoscio M, Harrower T, Young C, Lee M, Chhetri S, Ahmed F, Rog D, Silber E, Gallagher P, Duddy M, Straukiene A, Nicholas R, Rice C, Nixon SJ, Beveridge J, Hawton A, Tebbs S, Braisher M, Giovannoni G, Ciccarelli O, Greenwood J, Thompson AJ, Hunter R, Pavitt S, Pearson O, Evangelou N, Sharrack B, Galea I, Chandran S, Ford HL, Frost C, Chataway J. Blackstone J, et al. Among authors: galea i. BMJ Open. 2024 Sep 16;14(9):e086414. doi: 10.1136/bmjopen-2024-086414. BMJ Open. 2024. PMID: 39284697 Free PMC article. Clinical Trial.
Erythrocyte deformability correlates with systemic inflammation.
Jacob C, Piyasundara L, Bonello M, Nathan M, Kaninia S, Varatharaj A, Roy N, Galea I. Jacob C, et al. Among authors: galea i. Blood Cells Mol Dis. 2024 Nov;109:102881. doi: 10.1016/j.bcmd.2024.102881. Epub 2024 Aug 2. Blood Cells Mol Dis. 2024. PMID: 39151259 Free article.
Osmotic gradient ektacytometry - a novel diagnostic approach for neuroacanthocytosis syndromes.
Hernández CA, Peikert K, Qiao M, Darras A, de Wilde JRA, Bos J, Leibowitz M, Galea I, Wagner C, Rab MAE, Walker RH, Hermann A, van Beers EJ, van Wijk R, Kaestner L. Hernández CA, et al. Among authors: galea i. Front Neurosci. 2024 Jul 18;18:1406969. doi: 10.3389/fnins.2024.1406969. eCollection 2024. Front Neurosci. 2024. PMID: 39091345 Free PMC article.
Mild Systemic Inflammation Increases Erythrocyte Fragility.
Stuart CM, Jacob C, Varatharaj A, Howard S, Chouhan JK, Teeling JL, Galea I. Stuart CM, et al. Among authors: galea i. Int J Mol Sci. 2024 Jun 27;25(13):7027. doi: 10.3390/ijms25137027. Int J Mol Sci. 2024. PMID: 39000133 Free PMC article.
124 results