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DNA lesions that block transcription induce the death of Trypanosoma cruzi via ATR activation, which is dependent on the presence of R-loops.
Mendes IC, Dos Reis Bertoldo W, Miranda-Junior AS, Assis AV, Repolês BM, Ferreira WRR, Chame DF, Souza DL, Pavani RS, Macedo AM, Franco GR, Serra E, Perdomo V, Menck CFM, da Silva Leandro G, Fragoso SP, Barbosa Elias MCQ, Machado CR. Mendes IC, et al. Among authors: perdomo v. DNA Repair (Amst). 2024 Sep;141:103726. doi: 10.1016/j.dnarep.2024.103726. Epub 2024 Jul 27. DNA Repair (Amst). 2024. PMID: 39096697
Essential Bromodomain TcBDF2 as a Drug Target against Chagas Disease.
Pezza A, Tavernelli LE, Alonso VL, Perdomo V, Gabarro R, Prinjha R, Rodríguez Araya E, Rioja I, Docampo R, Calderón F, Martin J, Serra E. Pezza A, et al. Among authors: perdomo v. ACS Infect Dis. 2022 May 13;8(5):1062-1074. doi: 10.1021/acsinfecdis.2c00057. Epub 2022 Apr 28. ACS Infect Dis. 2022. PMID: 35482332
Intestinal ABC transporters: Influence on the metronomic cyclophosphamide-induced toxic effect in an obese mouse mammary cancer model.
Barranco MM, Zecchinati F, Perdomo VG, Habib MJ, Rico MJ, Rozados VR, Salazar M, Fusini ME, Scharovsky OG, Villanueva SSM, Mainetti LE, García F. Barranco MM, et al. Among authors: perdomo vg. Toxicol Appl Pharmacol. 2024 Nov;492:117130. doi: 10.1016/j.taap.2024.117130. Epub 2024 Oct 18. Toxicol Appl Pharmacol. 2024. PMID: 39426530
Reversion of down-regulation of intestinal multidrug resistance-associated protein 2 in fructose-fed rats by geraniol and vitamin C: Potential role of inflammatory response and oxidative stress.
Zecchinati F, Barranco MM, Arana MR, Tocchetti GN, Domínguez CJ, Perdomo VG, Ruiz ML, Mottino AD, García F, Villanueva SSM. Zecchinati F, et al. J Nutr Biochem. 2019 Jun;68:7-15. doi: 10.1016/j.jnutbio.2019.03.002. Epub 2019 Mar 19. J Nutr Biochem. 2019. PMID: 31005848
30 results