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Inhibition of the mitochondrial pyruvate carrier in astrocytes reduces amyloid and tau accumulation in the 3xTgAD mouse model of Alzheimer's disease.
Neurobiol Dis. 2024 Oct 1;200:106623. doi: 10.1016/j.nbd.2024.106623. Epub 2024 Aug 3.
Neurobiol Dis. 2024.
PMID: 39103022
Free article.
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases.
Nutma E, Fancy N, Weinert M, Tsartsalis S, Marzin MC, Muirhead RCJ, Falk I, Breur M, de Bruin J, Hollaus D, Pieterman R, Anink J, Story D, Chandran S, Tang J, Trolese MC, Saito T, Saido TC, Wiltshire KH, Beltran-Lobo P, Phillips A, Antel J, Healy L, Dorion MF, Galloway DA, Benoit RY, Amossé Q, Ceyzériat K, Badina AM, Kövari E, Bendotti C, Aronica E, Radulescu CI, Wong JH, Barron AM, Smith AM, Barnes SJ, Hampton DW, van der Valk P, Jacobson S, Howell OW, Baker D, Kipp M, Kaddatz H, Tournier BB, Millet P, Matthews PM, Moore CS, Amor S, Owen DR.
Nutma E, et al. Among authors: badina am.
Nat Commun. 2023 Aug 28;14(1):5247. doi: 10.1038/s41467-023-40937-z.
Nat Commun. 2023.
PMID: 37640701
Free PMC article.
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Low-Dose Radiation Therapy Impacts Microglial Inflammatory Response without Modulating Amyloid Load in Female TgF344-AD Rats.
Ceyzériat K, Jaques E, Gloria Y, Badina A, Millet P, Koutsouvelis N, Dipasquale G, Frisoni GB, Zilli T, Garibotto V, Tournier BB.
Ceyzériat K, et al.
J Alzheimers Dis. 2024;98(3):1001-1016. doi: 10.3233/JAD-231153.
J Alzheimers Dis. 2024.
PMID: 38489181
Free PMC article.
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Impairment of hippocampal astrocyte-mediated striatal dopamine release and locomotion in Alzheimer's disease.
Tournier BB, Ceyzériat K, Badina AM, Gloria Y, Fall AB, Amossé Q, Tsartsalis S, Millet P.
Tournier BB, et al. Among authors: badina am.
Neuroimage. 2024 Sep;298:120778. doi: 10.1016/j.neuroimage.2024.120778. Epub 2024 Aug 8.
Neuroimage. 2024.
PMID: 39122057
Free article.
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