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Angiopoietin-like 4 protects against endothelial dysfunction during bacterial sepsis.
Ziveri J, Le Guennec L, Dos Santos Souza I, Barnier JP, Walter SM, Diallo Y, Smail Y, Le Seac'h E, Bouzinba-Segard H, Faure C, Morand PC, Carel I, Perriere N, Schmitt T, Izac B, Letourneur F, Coureuil M, Rattei T, Nassif X, Bourdoulous S. Ziveri J, et al. Among authors: morand pc. Nat Microbiol. 2024 Sep;9(9):2434-2447. doi: 10.1038/s41564-024-01760-4. Epub 2024 Aug 5. Nat Microbiol. 2024. PMID: 39103571
Pathogenic Neisseria meningitidis utilizes CD147 for vascular colonization.
Bernard SC, Simpson N, Join-Lambert O, Federici C, Laran-Chich MP, Maïssa N, Bouzinba-Ségard H, Morand PC, Chretien F, Taouji S, Chevet E, Janel S, Lafont F, Coureuil M, Segura A, Niedergang F, Marullo S, Couraud PO, Nassif X, Bourdoulous S. Bernard SC, et al. Among authors: morand pc. Nat Med. 2014 Jul;20(7):725-31. doi: 10.1038/nm.3563. Epub 2014 Jun 1. Nat Med. 2014. PMID: 24880614 Free PMC article.
Strength of Neisseria meningitidis binding to endothelial cells requires highly-ordered CD147/β2-adrenoceptor clusters assembled by alpha-actinin-4.
Maïssa N, Covarelli V, Janel S, Durel B, Simpson N, Bernard SC, Pardo-Lopez L, Bouzinba-Ségard H, Faure C, Scott MGH, Coureuil M, Morand PC, Lafont F, Nassif X, Marullo S, Bourdoulous S. Maïssa N, et al. Among authors: morand pc. Nat Commun. 2017 Jun 1;8:15764. doi: 10.1038/ncomms15764. Nat Commun. 2017. PMID: 28569760 Free PMC article.
Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease.
Denis K, Le Bris M, Le Guennec L, Barnier JP, Faure C, Gouge A, Bouzinba-Ségard H, Jamet A, Euphrasie D, Durel B, Barois N, Pelissier P, Morand PC, Coureuil M, Lafont F, Join-Lambert O, Nassif X, Bourdoulous S. Denis K, et al. Among authors: morand pc. Nat Microbiol. 2019 Jun;4(6):972-984. doi: 10.1038/s41564-019-0395-8. Epub 2019 Mar 25. Nat Microbiol. 2019. PMID: 30911127
Meningococcus, this famous unknown.
Dos Santos Souza I, Ziveri J, Bouzinba-Segard H, Morand P, Bourdoulous S. Dos Santos Souza I, et al. C R Biol. 2021 Jul 2;344(2):127-143. doi: 10.5802/crbiol.56. C R Biol. 2021. PMID: 34213851 Free article.
The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus.
Barnier JP, Meyer J, Kolappan S, Bouzinba-Ségard H, Gesbert G, Jamet A, Frapy E, Schönherr-Hellec S, Capel E, Virion Z, Dupuis M, Bille E, Morand P, Schmitt T, Bourdoulous S, Nassif X, Craig L, Coureuil M. Barnier JP, et al. Proc Natl Acad Sci U S A. 2021 Nov 9;118(45):e2109364118. doi: 10.1073/pnas.2109364118. Proc Natl Acad Sci U S A. 2021. PMID: 34725157 Free PMC article.
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