Lei Q - Search Results

1

Design, synthesis and biological evaluation of naphthyl amide derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors.

Yu Q, Song C, Bi L, Zhao S, Lei Q, Yang N, Chen H, Wang Y, He Y, Deng H. Yu Q, et al. Among authors: lei q. Bioorg Med Chem. 2024 Sep 1;111:117844. doi: 10.1016/j.bmc.2024.117844. Epub 2024 Jul 23. Bioorg Med Chem. 2024. PMID: 39106652

2

Activity-based protein profiling: Recent advances in medicinal chemistry.

Deng H, Lei Q, Wu Y, He Y, Li W. Deng H, et al. Among authors: lei q. Eur J Med Chem. 2020 Apr 1;191:112151. doi: 10.1016/j.ejmech.2020.112151. Epub 2020 Feb 16. Eur J Med Chem. 2020. PMID: 32109778 Review.

3

Potential applications of clickable probes in EGFR activity visualization and prediction of EGFR-TKI therapy response for NSCLC patients.

Deng H, Lei Q, Shang W, Li Y, Bi L, Yang N, Yu Z, Li W. Deng H, et al. Among authors: lei q. Eur J Med Chem. 2022 Feb 15;230:114100. doi: 10.1016/j.ejmech.2022.114100. Epub 2022 Jan 4. Eur J Med Chem. 2022. PMID: 35007861

4

Discovering monoacylglycerol lipase inhibitors by a combination of fluorogenic substrate assay and activity-based protein profiling.

Deng H, Zhang Q, Lei Q, Yang N, Yang K, Jiang J, Yu Z. Deng H, et al. Among authors: lei q. Front Pharmacol. 2022 Aug 29;13:941522. doi: 10.3389/fphar.2022.941522. eCollection 2022. Front Pharmacol. 2022. PMID: 36105202 Free PMC article.

5

Therapeutic potential of targeting polo-like kinase 4.

Lei Q, Yu Q, Yang N, Xiao Z, Song C, Zhang R, Yang S, Liu Z, Deng H. Lei Q, et al. Eur J Med Chem. 2024 Feb 5;265:116115. doi: 10.1016/j.ejmech.2023.116115. Epub 2024 Jan 3. Eur J Med Chem. 2024. PMID: 38199166 Review.

6

Environment-Sensitive Fluorescent Probe Enables Assessment of Anaplastic Lymphoma Kinase Activity in Nonsmall Cell Lung Cancer.

Zhou X, Lei Q, Xiao Z, Song C, Deng H. Zhou X, et al. Among authors: lei q. Anal Chem. 2024 Feb 27;96(8):3525-3534. doi: 10.1021/acs.analchem.3c05337. Epub 2024 Feb 12. Anal Chem. 2024. PMID: 38345335

7

Expanded Application of a Photoaffinity Probe to Study Epidermal Growth Factor Receptor Tyrosine Kinase with Functional Activity.

Deng H, Lei Q, Yang N, Dai S, Peng H, Yang K, Xiao Z, Wang D, Yu Z, Li N, Li W. Deng H, et al. Among authors: lei q. Anal Chem. 2022 Jul 19;94(28):10118-10126. doi: 10.1021/acs.analchem.2c01340. Epub 2022 Jun 21. Anal Chem. 2022. PMID: 35729862

8

A fluorogenic probe for predicting treatment response in non-small cell lung cancer with EGFR-activating mutations.

Deng H, Lei Q, Wang C, Wang Z, Chen H, Wang G, Yang N, Huang D, Yu Q, Yao M, Xiao X, Zhu G, Cheng C, Li Y, Li F, Tian P, Li W. Deng H, et al. Among authors: lei q. Nat Commun. 2022 Nov 14;13(1):6944. doi: 10.1038/s41467-022-34627-5. Nat Commun. 2022. PMID: 36376325 Free PMC article.

9

Two-photon ratiometric fluorescent probe for imaging of hypochlorous acid in acute lung injury and its remediation effect.

Zhan Z, Chai L, Lei Q, Zhou X, Wang Y, Deng H, Lv Y, Li W. Zhan Z, et al. Among authors: lei q. Anal Chim Acta. 2021 Dec 1;1187:339159. doi: 10.1016/j.aca.2021.339159. Epub 2021 Oct 9. Anal Chim Acta. 2021. PMID: 34753573

10

Structural insights into targeting of the colchicine binding site by ELR510444 and parbendazole to achieve rational drug design.

Lei JH, Ma LL, Xian JH, Chen H, Zhou JJ, Chen H, Lei Q, Li YY, Wang YY, Wang YX. Lei JH, et al. Among authors: lei q. RSC Adv. 2021 May 25;11(31):18938-18944. doi: 10.1039/d1ra01173a. eCollection 2021 May 24. RSC Adv. 2021. PMID: 35478655 Free PMC article.

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