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HIV-1 interaction with an O-glycan-specific bacterial lectin enhances virus infectivity and resistance to neutralizing antibodies.
Heindel DW, Figueroa Acosta DM, Goff M, Yengo CK, Jan M, Liu X, Wang XH, Petrova MI, Zhang M, Sagar M, Barnette P, Pandey S, Hessell AJ, Chan KW, Kong XP, Chen BK, Mahal LK, Bensing BA, Hioe CE. Heindel DW, et al. Among authors: kong xp. iScience. 2024 Jun 27;27(8):110390. doi: 10.1016/j.isci.2024.110390. eCollection 2024 Aug 16. iScience. 2024. PMID: 39108723 Free PMC article.
HIV-1 interaction with an O-glycan-specific bacterial lectin enhances virus infectivity and resistance to neutralization by antibodies.
Heindel DW, Figueroa Acosta DM, Goff M, Yengo CK, Jan M, Liu X, Wang XH, Petrova MI, Zhang M, Sagar M, Barnette P, Pandey S, Hessell AJ, Chan KW, Kong XP, Chen BK, Mahal LK, Bensing BA, Hioe CE. Heindel DW, et al. Among authors: kong xp. Res Sq [Preprint]. 2024 Jan 3:rs.3.rs-2596269. doi: 10.21203/rs.3.rs-2596269/v2. Res Sq. 2024. Update in: iScience. 2024 Jun 27;27(8):110390. doi: 10.1016/j.isci.2024.110390 PMID: 36824869 Free PMC article. Updated. Preprint.
Structural insights reveal interplay between LAG-3 homodimerization, ligand binding, and function.
Silberstein JL, Du J, Chan KW, Frank JA, Mathews II, Kim YB, You J, Lu Q, Liu J, Philips EA, Liu P, Rao E, Fernandez D, Rodriguez GE, Kong XP, Wang J, Cochran JR. Silberstein JL, et al. Among authors: kong xp. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2310866121. doi: 10.1073/pnas.2310866121. Epub 2024 Mar 14. Proc Natl Acad Sci U S A. 2024. PMID: 38483996 Free PMC article.
Single-domain antibody-based protein degrader for synucleinopathies.
Jiang Y, Lin Y, Tetlow AM, Pan R, Ji C, Kong XP, Congdon EE, Sigurdsson EM. Jiang Y, et al. Among authors: kong xp. Mol Neurodegener. 2024 May 31;19(1):44. doi: 10.1186/s13024-024-00730-y. Mol Neurodegener. 2024. PMID: 38816762 Free PMC article.
Loss of HIV candidate vaccine efficacy in male macaques by mucosal nanoparticle immunization rescued by V2-specific response.
Rahman MA, Bissa M, Scinto H, Howe SE, Sarkis S, Ma ZM, Gutowska A, Jiang X, Luo CC, Schifanella L, Moles R, Silva de Castro I, Basu S, N'guessan KF, Williams LD, Becerra-Flores M, Doster MN, Hoang T, Choo-Wosoba H, Woode E, Sui Y, Tomaras GD, Paquin-Proulx D, Rao M, Talton JD, Kong XP, Zolla-Pazner S, Cardozo T, Franchini G, Berzofsky JA. Rahman MA, et al. Among authors: kong xp. Nat Commun. 2024 Oct 22;15(1):9102. doi: 10.1038/s41467-024-53359-2. Nat Commun. 2024. PMID: 39438480 Free PMC article.
Signal peptide exchange alters HIV-1 envelope antigenicity and immunogenicity.
Upadhyay C, Rao P, Behzadi MA, Feyznezhad R, Lambert GS, Kumar R, Kumar M, Yang W, Jiang X, Luo CC, Nadas A, Arthos J, Kong XP, Zhang H, Hioe CE, Duty JA. Upadhyay C, et al. Among authors: kong xp. Front Immunol. 2024 Sep 24;15:1476924. doi: 10.3389/fimmu.2024.1476924. eCollection 2024. Front Immunol. 2024. PMID: 39380992 Free PMC article.
Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains.
Wang S, Chan KW, Wei D, Ma X, Liu S, Hu G, Park S, Pan R, Gu Y, Nazzari AF, Olia AS, Xu K, Lin BC, Louder MK, McKee K, Doria-Rose NA, Montefiori D, Seaman MS, Zhou T, Kwong PD, Arthos J, Kong XP, Lu S. Wang S, et al. Among authors: kong xp. Nat Commun. 2024 May 21;15(1):4301. doi: 10.1038/s41467-024-48514-8. Nat Commun. 2024. PMID: 38773089 Free PMC article.
178 results