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Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques.
Edwards CT, Karunakaran KA, Garcia E, Beutler N, Gagne M, Golden N, Aoued H, Pellegrini KL, Burnett MR, Honeycutt CC, Lapp SA, Ton T, Lin MC, Metz A, Bombin A, Goff K, Scheuermann SE, Wilkes A, Wood JS, Ehnert S, Weissman S, Curran EH, Roy M, Dessasau E, Paiardini M, Upadhyay AA, Moore I, Maness NJ, Douek DC, Piantadosi A, Andrabi R, Rogers TR, Burton DR, Bosinger SE. Edwards CT, et al. Among authors: lapp sa. bioRxiv [Preprint]. 2024 Jul 30:2024.07.30.605768. doi: 10.1101/2024.07.30.605768. bioRxiv. 2024. PMID: 39109178 Free PMC article. Preprint.
Single cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells.
Moore KM, Pelletier AN, Lapp S, Metz A, Tharp GK, Lee M, Bhasin SS, Bhasin M, Sékaly RP, Bosinger SE, Suthar MS. Moore KM, et al. bioRxiv [Preprint]. 2024 Jan 21:2024.01.19.576293. doi: 10.1101/2024.01.19.576293. bioRxiv. 2024. Update in: J Virol. 2024 May 14;98(5):e0019424. doi: 10.1128/jvi.00194-24 PMID: 38293140 Free PMC article. Updated. Preprint.
Eosinophils protect against SARS-CoV-2 following a vaccine breakthrough infection.
Moore KM, Foster SL, Kar M, Floyd KA, Elrod EJ, Williams ME, Velden JV, Ellis M, Malik A, Wali B, Lapp S, Metz A, Bosinger SE, Menachery VD, Seder RA, Amara RR, Kohlmeier JE, Grakoui A, Suthar MS. Moore KM, et al. bioRxiv [Preprint]. 2024 Aug 10:2024.08.08.607190. doi: 10.1101/2024.08.08.607190. bioRxiv. 2024. PMID: 39211190 Free PMC article. Preprint.
Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence.
Strongin Z, Raymond Marchand L, Deleage C, Pampena MB, Cardenas MA, Beusch CM, Hoang TN, Urban EA, Gourves M, Nguyen K, Tharp GK, Lapp S, Rahmberg AR, Harper J, Del Rio Estrada PM, Gonzalez-Navarro M, Torres-Ruiz F, Luna-Villalobos YA, Avila-Rios S, Reyes-Teran G, Sekaly R, Silvestri G, Kulpa DA, Saez-Cirion A, Brenchley JM, Bosinger SE, Gordon DE, Betts MR, Kissick HT, Paiardini M. Strongin Z, et al. Nat Immunol. 2024 Jul;25(7):1245-1256. doi: 10.1038/s41590-024-01875-0. Epub 2024 Jun 17. Nat Immunol. 2024. PMID: 38886592
Malaria disrupts the rhesus macaque gut microbiome.
Farinella DN, Kaur S, Tran V, Cabrera-Mora M, Joyner CJ, Lapp SA, Pakala SB, Nural MV, DeBarry JD, Kissinger JC, Jones DP, Moreno A, Galinski MR, Cordy RJ. Farinella DN, et al. Among authors: lapp sa. Front Cell Infect Microbiol. 2023 Jan 13;12:1058926. doi: 10.3389/fcimb.2022.1058926. eCollection 2022. Front Cell Infect Microbiol. 2023. PMID: 36710962 Free PMC article.
MaHPIC malaria systems biology data from Plasmodium cynomolgi sporozoite longitudinal infections in macaques.
DeBarry JD, Nural MV, Pakala SB, Nayak V, Warrenfeltz S, Humphrey J, Lapp SA, Cabrera-Mora M, Brito CFA, Jiang J, Saney CL, Hankus A, Stealey HM, DeBarry MB, Lackman N, Legall N, Lee K, Tang Y, Gupta A, Trippe ED, Bridger RR, Weatherly DB, Peterson MS, Jiang X, Tran V, Uppal K, Fonseca LL, Joyner CJ, Karpuzoglu E, Cordy RJ, Meyer EVS, Wells LL, Ory DS, Lee FE, Tirouvanziam R, Gutiérrez JB, Ibegbu C, Lamb TJ, Pohl J, Pruett ST, Jones DP, Styczynski MP, Voit EO, Moreno A, Galinski MR, Kissinger JC. DeBarry JD, et al. Among authors: lapp sa. Sci Data. 2022 Nov 24;9(1):722. doi: 10.1038/s41597-022-01755-y. Sci Data. 2022. PMID: 36433985 Free PMC article.
An RSV Live-Attenuated Vaccine Candidate Lacking G Protein Mucin Domains Is Attenuated, Immunogenic, and Effective in Preventing RSV in BALB/c Mice.
Roe MK, Perez MA, Hsiao HM, Lapp SA, Sun HY, Jadhao S, Young AR, Batista YS, Reed RC, Taz A, Piantadosi A, Chen X, Liang B, Koval M, Snider TA, Moore ML, Anderson EJ, Anderson LJ, Stobart CC, Rostad CA. Roe MK, et al. Among authors: lapp sa. J Infect Dis. 2022 Dec 28;227(1):50-60. doi: 10.1093/infdis/jiac382. J Infect Dis. 2022. PMID: 36281651 Free PMC article.
Plasmodium knowlesi Cytoadhesion Involves SICA Variant Proteins.
Peterson MS, Joyner CJ, Lapp SA, Brady JA, Wood JS, Cabrera-Mora M, Saney CL, Fonseca LL, Cheng WT, Jiang J, Soderberg SR, Nural MV, Hankus A, Machiah D, Karpuzoglu E, DeBarry JD, Tirouvanziam R, Kissinger JC, Moreno A, Gumber S, Voit EO, Gutierrez JB, Cordy RJ, Galinski MR. Peterson MS, et al. Among authors: lapp sa. Front Cell Infect Microbiol. 2022 Jun 23;12:888496. doi: 10.3389/fcimb.2022.888496. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 35811680 Free PMC article.
36 results