Witney TH - Search Results

1

(SiFA)SeFe: A Hydrophilic Silicon-Based Fluoride Acceptor Enabling Versatile Peptidic Radiohybrid Tracers.

Deiser S, Fenzl S, König V, Drexler M, Smith LM, George ME, Beck R, Witney TH, Inoue S, Casini A. Deiser S, et al. Among authors: witney th. J Med Chem. 2024 Aug 22;67(16):14077-14094. doi: 10.1021/acs.jmedchem.4c00924. Epub 2024 Aug 8. J Med Chem. 2024. PMID: 39115131 Free PMC article.

2

Imaging the master regulator of the antioxidant response in non-small cell lung cancer with positron emission tomography.

Greenwood HE, Edwards RS, Tyrrell WE, Barber AR, Baark F, Tanc M, Khalil E, Falzone A, Ward NP, DeBlasi JM, Torrente L, Pearce DR, Firth G, Smith LM, Timmermand OV, Huebner A, George ME, Swanton C, Hynds RE, DeNicola GM, Witney TH. Greenwood HE, et al. Among authors: witney th. bioRxiv [Preprint]. 2023 Dec 17:2023.12.16.572007. doi: 10.1101/2023.12.16.572007. bioRxiv. 2023. PMID: 38168428 Free PMC article. Preprint.

3

The chicken chorioallantoic membrane as a low-cost, high-throughput model for cancer imaging.

Smith LM, Greenwood HE, Tyrrell WE, Edwards RS, de Santis V, Baark F, Firth G, Tanc M, Terry SYA, Herrmann A, Southworth R, Witney TH. Smith LM, et al. Among authors: witney th. Npj Imaging. 2023 Nov 29;1(1):1. doi: 10.1038/s44303-023-00001-3. Npj Imaging. 2023. PMID: 38239706 Free PMC article.

4

Is System x_c^- a Suitable Target for Tumour Detection and Response Assessment with Imaging?

Sharkey AR, Witney TH, Cook GJR. Sharkey AR, et al. Among authors: witney th. Cancers (Basel). 2023 Nov 24;15(23):5573. doi: 10.3390/cancers15235573. Cancers (Basel). 2023. PMID: 38067277 Free PMC article. Review.

5

One-Pot Radiosynthesis and Biological Evaluation of a Caspase-3 Selective 5-[^123,125I]iodo-1,2,3-triazole derived Isatin SPECT Tracer.

Glaser M, Rajkumar V, Diocou S, Gendron T, Yan R, Sin PKB, Sander K, Carroll L, Pedley RB, Aboagye EO, Witney TH, Årstad E. Glaser M, et al. Among authors: witney th. Sci Rep. 2019 Dec 17;9(1):19299. doi: 10.1038/s41598-019-55992-0. Sci Rep. 2019. PMID: 31848442 Free PMC article.

6

Clinical [¹⁸F]FSPG Positron Emission Tomography Imaging Reveals Heterogeneity in Tumor-Associated System x_c^- Activity.

Sharkey AR, Koglin N, Mittra ES, Han S, Cook GJR, Witney TH. Sharkey AR, et al. Among authors: witney th. Cancers (Basel). 2024 Apr 8;16(7):1437. doi: 10.3390/cancers16071437. Cancers (Basel). 2024. PMID: 38611114 Free PMC article.

7

Radiotracer stereochemistry affects substrate affinity and kinetics for improved imaging of system x_C^- in tumors.

Greenwood HE, Edwards R, Koglin N, Berndt M, Baark F, Kim J, Firth G, Khalil E, Mueller A, Witney TH. Greenwood HE, et al. Among authors: witney th. Theranostics. 2022 Jan 24;12(4):1921-1936. doi: 10.7150/thno.63237. eCollection 2022. Theranostics. 2022. PMID: 35198080 Free PMC article.

8

Robust and Facile Automated Radiosynthesis of [¹⁸F]FSPG on the GE FASTlab.

Edwards R, Greenwood HE, McRobbie G, Khan I, Witney TH. Edwards R, et al. Among authors: witney th. Mol Imaging Biol. 2021 Dec;23(6):854-864. doi: 10.1007/s11307-021-01609-w. Epub 2021 May 20. Mol Imaging Biol. 2021. PMID: 34013395 Free PMC article.

9

The chemical tool-kit for molecular imaging with radionuclides in the age of targeted and immune therapy.

Witney TH, Blower PJ. Witney TH, et al. Cancer Imaging. 2021 Jan 30;21(1):18. doi: 10.1186/s40644-021-00385-8. Cancer Imaging. 2021. PMID: 33516256 Free PMC article. Review.

10

Mapping Aldehyde Dehydrogenase 1A1 Activity using an [¹⁸ F]Substrate-Based Approach.

Pereira R, Gendron T, Sanghera C, Greenwood HE, Newcombe J, McCormick PN, Sander K, Topf M, Årstad E, Witney TH. Pereira R, et al. Among authors: witney th. Chemistry. 2019 Feb 11;25(9):2345-2351. doi: 10.1002/chem.201805473. Epub 2019 Jan 14. Chemistry. 2019. PMID: 30521138 Free PMC article.

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