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A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants.
Metzdorf K, Jacobsen H, Kim Y, Teixeira Alves LG, Kulkarni U, Brdovčak MC, Materljan J, Eschke K, Chaudhry MZ, Hoffmann M, Bertoglio F, Ruschig M, Hust M, Šustić M, Krmpotić A, Jonjić S, Widera M, Ciesek S, Pöhlmann S, Landthaler M, Čičin-Šain L. Metzdorf K, et al. Among authors: ciesek s. Front Immunol. 2024 Jul 25;15:1383086. doi: 10.3389/fimmu.2024.1383086. eCollection 2024. Front Immunol. 2024. PMID: 39119342 Free PMC article.
A single-dose MCMV-based vaccine elicits long-lasting immune protection in mice against distinct SARS-CoV-2 variants.
Metzdorf K, Jacobsen H, Kim Y, Teixeira Alves LG, Kulkarni U, Eschke K, Chaudhry MZ, Hoffmann M, Bertoglio F, Ruschig M, Hust M, Cokarić Brdovčak M, Materljan J, Šustić M, Krmpotić A, Jonjić S, Widera M, Ciesek S, Pöhlmann S, Landthaler M, Čičin-Šain L. Metzdorf K, et al. Among authors: ciesek s. bioRxiv [Preprint]. 2024 Feb 15:2022.11.25.517953. doi: 10.1101/2022.11.25.517953. bioRxiv. 2024. Update in: Front Immunol. 2024 Jul 25;15:1383086. doi: 10.3389/fimmu.2024.1383086 PMID: 36482969 Free PMC article. Updated. Preprint.
A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS-CoV-2 infection model.
Peter AS, Roth E, Schulz SR, Fraedrich K, Steinmetz T, Damm D, Hauke M, Richel E, Mueller-Schmucker S, Habenicht K, Eberlein V, Issmail L, Uhlig N, Dolles S, Grüner E, Peterhoff D, Ciesek S, Hoffmann M, Pöhlmann S, McKay PF, Shattock RJ, Wölfel R, Socher E, Wagner R, Eichler J, Sticht H, Schuh W, Neipel F, Ensser A, Mielenz D, Tenbusch M, Winkler TH, Grunwald T, Überla K, Jäck HM. Peter AS, et al. Among authors: ciesek s. Eur J Immunol. 2022 May;52(5):770-783. doi: 10.1002/eji.202149374. Epub 2021 Sep 13. Eur J Immunol. 2022. PMID: 34355795 Free PMC article.
Efficacy of an unmodified bivalent mRNA vaccine against SARS-CoV-2 variants in female small animal models.
Corleis B, Hoffmann D, Rauch S, Fricke C, Roth N, Gergen J, Kovacikova K, Schlottau K, Halwe NJ, Ulrich L, Schön J, Wernike K, Widera M, Ciesek S, Mueller SO, Mettenleiter TC, Maione D, Petsch B, Beer M, Dorhoi A. Corleis B, et al. Among authors: ciesek s. Nat Commun. 2023 Feb 13;14(1):816. doi: 10.1038/s41467-023-36110-1. Nat Commun. 2023. PMID: 36781853 Free PMC article.
TMPRSS2 Is Essential for SARS-CoV-2 Beta and Omicron Infection.
Metzdorf K, Jacobsen H, Greweling-Pils MC, Hoffmann M, Lüddecke T, Miller F, Melcher L, Kempf AM, Nehlmeier I, Bruder D, Widera M, Ciesek S, Pöhlmann S, Čičin-Šain L. Metzdorf K, et al. Among authors: ciesek s. Viruses. 2023 Jan 18;15(2):271. doi: 10.3390/v15020271. Viruses. 2023. PMID: 36851486 Free PMC article.
Intranasal Administration of a Monoclonal Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection.
Halwe S, Kupke A, Vanshylla K, Liberta F, Gruell H, Zehner M, Rohde C, Krähling V, Gellhorn Serra M, Kreer C, Klüver M, Sauerhering L, Schmidt J, Cai Z, Han F, Young D, Yang G, Widera M, Koch M, Werner A, Kämper L, Becker N, Marlow MS, Eickmann M, Ciesek S, Schiele F, Klein F, Becker S. Halwe S, et al. Among authors: ciesek s. Viruses. 2021 Jul 29;13(8):1498. doi: 10.3390/v13081498. Viruses. 2021. PMID: 34452363 Free PMC article.
Limited neutralisation of the SARS-CoV-2 Omicron subvariants BA.1 and BA.2 by convalescent and vaccine serum and monoclonal antibodies.
Wilhelm A, Widera M, Grikscheit K, Toptan T, Schenk B, Pallas C, Metzler M, Kohmer N, Hoehl S, Marschalek R, Herrmann E, Helfritz FA, Wolf T, Goetsch U, Ciesek S. Wilhelm A, et al. Among authors: ciesek s. EBioMedicine. 2022 Aug;82:104158. doi: 10.1016/j.ebiom.2022.104158. Epub 2022 Jul 11. EBioMedicine. 2022. PMID: 35834885 Free PMC article.
227 results