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Overexpression of Toxic Poly(Glycine-Alanine) Aggregates in Primary Neuronal Cultures Induces Time-Dependent Autophagic and Synaptic Alterations but Subtle Activity Impairments.
Cells. 2024 Aug 3;13(15):1300. doi: 10.3390/cells13151300.
Cells. 2024.
PMID: 39120329
Free PMC article.
Heterozygous knockout of Synaptotagmin13 phenocopies ALS features and TP53 activation in human motor neurons.
Lehmann J, Aly A, Steffke C, Fabbio L, Mayer V, Dikwella N, Halablab K, Roselli F, Seiffert S, Boeckers TM, Brenner D, Kabashi E, Mulaw M, Ho R, Catanese A.
Lehmann J, et al. Among authors: steffke c.
Cell Death Dis. 2024 Aug 3;15(8):560. doi: 10.1038/s41419-024-06957-3.
Cell Death Dis. 2024.
PMID: 39097602
Free PMC article.
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Propranolol reduces the accumulation of cytotoxic aggregates in C9orf72-ALS/FTD in vitro models.
Seidel M, Rajkumar S, Steffke C, Noeth V, Agarwal S, Roger K, Lipecka J, Ludolph A, Guerrera CI, Boeckers T, Catanese A.
Seidel M, et al. Among authors: steffke c.
Curr Res Neurobiol. 2023 Jul 30;5:100105. doi: 10.1016/j.crneur.2023.100105. eCollection 2023.
Curr Res Neurobiol. 2023.
PMID: 37576491
Free PMC article.
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