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A secondary β-hydroxybutyrate metabolic pathway linked to energy balance.
Moya-Garzon MD, Wang M, Li VL, Lyu X, Wei W, Tung AS, Raun SH, Zhao M, Coassolo L, Islam H, Oliveira B, Dai Y, Spaas J, Delgado-Gonzalez A, Donoso K, Alvarez-Buylla A, Franco-Montalban F, Letian A, Ward C, Liu L, Svensson KJ, Goldberg EL, Gardner CD, Little JP, Banik SM, Xu Y, Long JZ. Moya-Garzon MD, et al. Among authors: spaas j. bioRxiv [Preprint]. 2024 Sep 9:2024.09.09.612087. doi: 10.1101/2024.09.09.612087. bioRxiv. 2024. PMID: 39314488 Free PMC article. Preprint.
A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites.
Moya-Garzon MD, Wang M, Li VL, Lyu X, Wei W, Tung AS, Raun SH, Zhao M, Coassolo L, Islam H, Oliveira B, Dai Y, Spaas J, Delgado-Gonzalez A, Donoso K, Alvarez-Buylla A, Franco-Montalban F, Letian A, Ward CP, Liu L, Svensson KJ, Goldberg EL, Gardner CD, Little JP, Banik SM, Xu Y, Long JZ. Moya-Garzon MD, et al. Among authors: spaas j. Cell. 2025 Jan 9;188(1):175-186.e20. doi: 10.1016/j.cell.2024.10.032. Epub 2024 Nov 12. Cell. 2025. PMID: 39536746 Free article.
Equine allogeneic tenogenic primed mesenchymal stem cells: A clinical field study in horses suffering from naturally occurring superficial digital flexor tendon and suspensory ligament injuries.
Carlier S, Depuydt E, Suls M, Bocqué C, Thys J, Vandenberghe A, Martens A, Saunders J, Hellmann K, Braun G, Beerts C, Spaas JH. Carlier S, et al. Among authors: spaas jh. Equine Vet J. 2024 Sep;56(5):924-935. doi: 10.1111/evj.14008. Epub 2023 Oct 17. Equine Vet J. 2024. PMID: 37847100
Low-dose xenogeneic mesenchymal stem cells target canine osteoarthritis through systemic immunomodulation and homing.
Beerts C, Broeckx SY, Depuydt E, Tack L, Van Hecke L, Chiers K, Van Brantegem L, Braun G, Hellmann K, de Bouvre N, Van Bruaene N, De Ryck T, Duchateau L, Van Ryssen B, Peremans K, Saunders JH, Verhoeven G, Pauwelyn G, Spaas JH. Beerts C, et al. Among authors: spaas jh. Arthritis Res Ther. 2023 Oct 3;25(1):190. doi: 10.1186/s13075-023-03168-7. Arthritis Res Ther. 2023. PMID: 37789403 Free PMC article.
Carnosine synthase deficiency aggravates neuroinflammation in multiple sclerosis.
Spaas J, Van der Stede T, de Jager S, van de Waterweg Berends A, Tiane A, Baelde H, Baba SP, Eckhardt M, Wolfs E, Vanmierlo T, Hellings N, Eijnde BO, Derave W. Spaas J, et al. Prog Neurobiol. 2023 Dec;231:102532. doi: 10.1016/j.pneurobio.2023.102532. Epub 2023 Sep 27. Prog Neurobiol. 2023. PMID: 37774767
Extensive profiling of histidine-containing dipeptides reveals species- and tissue-specific distribution and metabolism in mice, rats, and humans.
Van der Stede T, Spaas J, de Jager S, De Brandt J, Hansen C, Stautemas J, Vercammen B, De Baere S, Croubels S, Van Assche CH, Pastor BC, Vandenbosch M, Van Thienen R, Verboven K, Hansen D, Bové T, Lapauw B, Van Praet C, Decaestecker K, Vanaudenaerde B, Eijnde BO, Gliemann L, Hellsten Y, Derave W. Van der Stede T, et al. Among authors: spaas j. Acta Physiol (Oxf). 2023 Sep;239(1):e14020. doi: 10.1111/apha.14020. Epub 2023 Jul 24. Acta Physiol (Oxf). 2023. PMID: 37485756
70 results