The gut-brain axis underlying hepatic encephalopathy in liver cirrhosis.
He X, Hu M, Xu Y, Xia F, Tan Y, Wang Y, Xiang H, Wu H, Ji T, Xu Q, Wang L, Huang Z, Sun M, Wan Y, Cui P, Liang S, Pan Y, Xiao S, He Y, Song R, Yan J, Quan X, Wei Y, Hong C, Liao W, Li F, El-Omar E, Chen J, Qi X, Gao J, Zhou H.
He X, et al.
Nat Med. 2025 Jan 8. doi: 10.1038/s41591-024-03405-9. Online ahead of print.
Nat Med. 2025.
PMID: 39779925
This accumulation of PEA was primarily driven by decreased monoamine oxidase-B activity in both the liver and serum due to cirrhosis. Targeting PDC or PEA reversed the neurological symptoms induced by R. gnavus. ...
This accumulation of PEA was primarily driven by decreased monoamine oxidase-B activity in both the liver and serum due to cir …