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Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction.
Li Q, Feng H, Wang H, Wang Y, Mou W, Xu G, Zhang P, Li R, Shi W, Wang Z, Fang Z, Ren L, Wang Y, Lin L, Hou X, Dai W, Li Z, Wei Z, Liu T, Wang J, Guo Y, Li P, Zhao X, Zhan X, Xiao X, Bai Z. Li Q, et al. Among authors: wang h, wang z, wang j, wang y. EMBO Rep. 2022 Feb 3;23(2):e53499. doi: 10.15252/embr.202153499. Epub 2021 Dec 9. EMBO Rep. 2022. PMID: 34882936 Free PMC article.
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