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Page 1
The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2.
Suryawanshi RK, Jaishankar P, Correy GJ, Rachman MM, O'Leary PC, Taha TY, Zapatero-Belinchón FJ, McCavittMalvido M, Doruk YU, Stevens MGV, Diolaiti ME, Jogalekar MP, Richards AL, Montano M, Rosecrans J, Matthay M, Togo T, Gonciarz RL, Gopalkrishnan S, Neitz RJ, Krogan NJ, Swaney DL, Shoichet BK, Ott M, Renslo AR, Ashworth A, Fraser JS. Suryawanshi RK, et al. Among authors: togo t. bioRxiv [Preprint]. 2024 Aug 29:2024.08.08.606661. doi: 10.1101/2024.08.08.606661. bioRxiv. 2024. PMID: 39149230 Free PMC article. Preprint.
Extensive exploration of structure activity relationships for the SARS-CoV-2 macrodomain from shape-based fragment merging and active learning.
Correy GJ, Rachman M, Togo T, Gahbauer S, Doruk YU, Stevens M, Jaishankar P, Kelley B, Goldman B, Schmidt M, Kramer T, Ashworth A, Riley P, Shoichet BK, Renslo AR, Walters WP, Fraser JS. Correy GJ, et al. Among authors: togo t. bioRxiv [Preprint]. 2024 Aug 26:2024.08.25.609621. doi: 10.1101/2024.08.25.609621. bioRxiv. 2024. PMID: 39253507 Free PMC article. Preprint.
Expanding Automated Multiconformer Ligand Modeling to Macrocycles and Fragments.
Flowers J, Echols N, Correy G, Jaishankar P, Togo T, Renslo AR, van den Bedem H, Fraser JS, Wankowicz SA. Flowers J, et al. Among authors: togo t. bioRxiv [Preprint]. 2024 Sep 23:2024.09.20.613996. doi: 10.1101/2024.09.20.613996. bioRxiv. 2024. PMID: 39386683 Free PMC article. Preprint.
Orthotopic transplantation of the bioengineered lung using a mouse-scale perfusion-based bioreactor and human primary endothelial cells.
Tomiyama F, Suzuki T, Watanabe T, Miyanaga J, Suzuki A, Ito T, Murai S, Suzuki Y, Niikawa H, Oishi H, Notsuda H, Watanabe Y, Hirama T, Onodera K, Togo T, Noda M, Waddell TK, Karoubi G, Okada Y. Tomiyama F, et al. Among authors: togo t. Sci Rep. 2024 Apr 4;14(1):7040. doi: 10.1038/s41598-024-57084-0. Sci Rep. 2024. PMID: 38575597 Free PMC article.
Pharmacological intervention of cholesterol sulfate-mediated T cell exclusion promotes antitumor immunity.
Tatsuguchi T, Uruno T, Sugiura Y, Oisaki K, Takaya D, Sakata D, Izumi Y, Togo T, Hattori Y, Kunimura K, Sakurai T, Honma T, Bamba T, Nakamura M, Kanai M, Suematsu M, Fukui Y. Tatsuguchi T, et al. Among authors: togo t. Biochem Biophys Res Commun. 2022 Jun 18;609:183-188. doi: 10.1016/j.bbrc.2022.04.035. Epub 2022 Apr 10. Biochem Biophys Res Commun. 2022. PMID: 35452959 Free article.
Intralymphatic immunotherapy with one or two allergens renders similar clinical response in patients with allergic rhinitis due to birch and grass pollen.
Ahlbeck L, Ahlberg E, Björkander J, Aldén C, Papapavlou G, Palmberg L, Nyström U, Retsas P, Nordenfelt P, Togö T, Johansen P, Rolander B, Duchén K, Jenmalm MC. Ahlbeck L, et al. Among authors: togo t. Clin Exp Allergy. 2022 Jun;52(6):747-759. doi: 10.1111/cea.14138. Epub 2022 Apr 1. Clin Exp Allergy. 2022. PMID: 35332591 Free PMC article. Clinical Trial.
182 results