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4-Phenylbutyrate promoted wild-type γ-aminobutyric acid type A receptor trafficking, reduced endoplasmic reticulum stress, and mitigated seizures in Gabrg2+/Q390X mice associated with Dravet syndrome.
Shen W, Flamm C, Delahanty AJ, Casteel E, Biven M, DeLeeuw MB, Poliquin S, Nwosu G, Randhave K, Kang JQ. Shen W, et al. Among authors: deleeuw mb. Epilepsia. 2024 Jan;65(1):204-217. doi: 10.1111/epi.17779. Epub 2023 Nov 29. Epilepsia. 2024. PMID: 37746768 Free PMC article.