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Crystal structure of native β-N-acetylhexosaminidase isolated from Aspergillus oryzae sheds light onto its substrate specificity, high stability, and regulation by propeptide.
Škerlová J, Bláha J, Pachl P, Hofbauerová K, Kukačka Z, Man P, Pompach P, Novák P, Otwinowski Z, Brynda J, Vaněk O, Řezáčová P. Škerlová J, et al. Among authors: novak p. FEBS J. 2018 Feb;285(3):580-598. doi: 10.1111/febs.14360. Epub 2017 Dec 30. FEBS J. 2018. PMID: 29239122 Free article.
Molecular Mechanism of LEDGF/p75 Dimerization.
Lux V, Brouns T, Čermáková K, Srb P, Fábry M, Mádlíková M, Hořejší M, Kukačka Z, Novák P, Kugler M, Brynda J, DeRijck J, Christ F, Debyser Z, Veverka V. Lux V, et al. Among authors: novak p. Structure. 2020 Dec 1;28(12):1288-1299.e7. doi: 10.1016/j.str.2020.08.012. Epub 2020 Sep 17. Structure. 2020. PMID: 32946742 Free article.
Multivalency of nucleosome recognition by LEDGF.
Koutná E, Lux V, Kouba T, Škerlová J, Nováček J, Srb P, Hexnerová R, Šváchová H, Kukačka Z, Novák P, Fábry M, Poepsel S, Veverka V. Koutná E, et al. Among authors: novak p. Nucleic Acids Res. 2023 Oct 13;51(18):10011-10025. doi: 10.1093/nar/gkad674. Nucleic Acids Res. 2023. PMID: 37615563 Free PMC article.
Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice.
Vanek O, Nálezková M, Kavan D, Borovicková I, Pompach P, Novák P, Kumar V, Vannucci L, Hudecek J, Hofbauerová K, Kopecký V Jr, Brynda J, Kolenko P, Dohnálek J, Kaderávek P, Chmelík J, Gorcík L, Zídek L, Sklenár V, Bezouska K. Vanek O, et al. Among authors: novak p. FEBS J. 2008 Nov;275(22):5589-606. doi: 10.1111/j.1742-4658.2008.06683.x. FEBS J. 2008. PMID: 18959746 Free article.
1,119 results