Foo T - Search Results

1

DSS1 restrains BRCA2's engagement with dsDNA for homologous recombination, replication fork protection, and R-loop homeostasis.

Huang Y, Li W, Foo T, Ji JH, Wu B, Tomimatsu N, Fang Q, Gao B, Long M, Xu J, Maqbool R, Mukherjee B, Ni T, Alejo S, He Y, Burma S, Lan L, Xia B, Zhao W. Huang Y, et al. Among authors: foo t. Nat Commun. 2024 Aug 17;15(1):7081. doi: 10.1038/s41467-024-51557-6. Nat Commun. 2024. PMID: 39152168 Free PMC article.

2

BRCA1-Dependent and Independent Recruitment of PALB2-BRCA2-RAD51 in the DNA Damage Response and Cancer.

Foo TK, Xia B. Foo TK, et al. Cancer Res. 2022 Sep 16;82(18):3191-3197. doi: 10.1158/0008-5472.CAN-22-1535. Cancer Res. 2022. PMID: 35819255 Free PMC article. Review.

3

BRCA2 associates with MCM10 to suppress PRIMPOL-mediated repriming and single-stranded gap formation after DNA damage.

Kang Z, Fu P, Alcivar AL, Fu H, Redon C, Foo TK, Zuo Y, Ye C, Baxley R, Madireddy A, Buisson R, Bielinsky AK, Zou L, Shen Z, Aladjem MI, Xia B. Kang Z, et al. Nat Commun. 2021 Oct 13;12(1):5966. doi: 10.1038/s41467-021-26227-6. Nat Commun. 2021. PMID: 34645815 Free PMC article.

4

Functional and mutational landscapes of BRCA1 for homology-directed repair and therapy resistance.

Anantha RW, Simhadri S, Foo TK, Miao S, Liu J, Shen Z, Ganesan S, Xia B. Anantha RW, et al. Elife. 2017 Apr 11;6:e21350. doi: 10.7554/eLife.21350. Elife. 2017. PMID: 28398198 Free PMC article.

5

ATR/ATM-Mediated Phosphorylation of BRCA1 T1394 Promotes Homologous Recombinational Repair and G₂-M Checkpoint Maintenance.

Foo TK, Vincelli G, Huselid E, Her J, Zheng H, Simhadri S, Wang M, Huo Y, Li T, Yu X, Li H, Zhao W, Bunting SF, Xia B. Foo TK, et al. Cancer Res. 2021 Sep 15;81(18):4676-4684. doi: 10.1158/0008-5472.CAN-20-2723. Epub 2021 Jul 23. Cancer Res. 2021. PMID: 34301763 Free PMC article.

6

Disrupted BRCA1-PALB2 interaction induces tumor immunosuppression and T-lymphocyte infiltration in HCC through cGAS-STING pathway.

Ma H, Kang Z, Foo TK, Shen Z, Xia B. Ma H, et al. Hepatology. 2023 Jan 1;77(1):33-47. doi: 10.1002/hep.32335. Epub 2022 Feb 15. Hepatology. 2023. PMID: 35006619 Free PMC article.

7

Coupling of Homologous Recombination and the Checkpoint by ATR.

Buisson R, Niraj J, Rodrigue A, Ho CK, Kreuzer J, Foo TK, Hardy EJ, Dellaire G, Haas W, Xia B, Masson JY, Zou L. Buisson R, et al. Mol Cell. 2017 Jan 19;65(2):336-346. doi: 10.1016/j.molcel.2016.12.007. Epub 2017 Jan 12. Mol Cell. 2017. PMID: 28089683 Free PMC article.

8

Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites.

Wu Q, Paul A, Su D, Mehmood S, Foo TK, Ochi T, Bunting EL, Xia B, Robinson CV, Wang B, Blundell TL. Wu Q, et al. Among authors: foo tk. Mol Cell. 2016 Feb 4;61(3):434-448. doi: 10.1016/j.molcel.2015.12.017. Epub 2016 Jan 14. Mol Cell. 2016. PMID: 26778126 Free PMC article.

9

PALB2 connects BRCA1 and BRCA2 in the G2/M checkpoint response.

Simhadri S, Vincelli G, Huo Y, Misenko S, Foo TK, Ahlskog J, Sørensen CS, Oakley GG, Ganesan S, Bunting SF, Xia B. Simhadri S, et al. Oncogene. 2019 Mar;38(10):1585-1596. doi: 10.1038/s41388-018-0535-2. Epub 2018 Oct 18. Oncogene. 2019. PMID: 30337689 Free PMC article.

10

Functional characterization of 84 PALB2 variants of uncertain significance.

Wiltshire T, Ducy M, Foo TK, Hu C, Lee KY, Belur Nagaraj A, Rodrigue A, Gomes TT, Simard J, Monteiro ANA, Xia B, Carvalho MA, Masson JY, Couch FJ. Wiltshire T, et al. Among authors: foo tk. Genet Med. 2020 Mar;22(3):622-632. doi: 10.1038/s41436-019-0682-z. Epub 2019 Oct 21. Genet Med. 2020. PMID: 31636395 Free PMC article.

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