Lan L - Search Results

1

DSS1 restrains BRCA2's engagement with dsDNA for homologous recombination, replication fork protection, and R-loop homeostasis.

Huang Y, Li W, Foo T, Ji JH, Wu B, Tomimatsu N, Fang Q, Gao B, Long M, Xu J, Maqbool R, Mukherjee B, Ni T, Alejo S, He Y, Burma S, Lan L, Xia B, Zhao W. Huang Y, et al. Among authors: lan l. Nat Commun. 2024 Aug 17;15(1):7081. doi: 10.1038/s41467-024-51557-6. Nat Commun. 2024. PMID: 39152168 Free PMC article.

2

ROS-induced R loops trigger a transcription-coupled but BRCA1/2-independent homologous recombination pathway through CSB.

Teng Y, Yadav T, Duan M, Tan J, Xiang Y, Gao B, Xu J, Liang Z, Liu Y, Nakajima S, Shi Y, Levine AS, Zou L, Lan L. Teng Y, et al. Among authors: lan l. Nat Commun. 2018 Oct 8;9(1):4115. doi: 10.1038/s41467-018-06586-3. Nat Commun. 2018. PMID: 30297739 Free PMC article.

3

Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair.

Wang Y, Gao B, Zhang L, Wang X, Zhu X, Yang H, Zhang F, Zhu X, Zhou B, Yao S, Nagayama A, Lee S, Ouyang J, Koh SB, Eisenhauer EL, Zarrella D, Lu K, Rueda BR, Zou L, Su XA, Yeku O, Ellisen LW, Wang XS, Lan L. Wang Y, et al. Among authors: lan l. Nat Commun. 2024 Feb 21;15(1):1568. doi: 10.1038/s41467-024-45693-2. Nat Commun. 2024. PMID: 38383600 Free PMC article.

4

The RNA m5C modification in R-loops as an off switch of Alt-NHEJ.

Yang H, Lachtara EM, Ran X, Hopkins J, Patel PS, Zhu X, Xiao Y, Phoon L, Gao B, Zou L, Lawrence MS, Lan L. Yang H, et al. Among authors: lan l. Nat Commun. 2023 Sep 30;14(1):6114. doi: 10.1038/s41467-023-41790-w. Nat Commun. 2023. PMID: 37777505 Free PMC article.

5

HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β.

Fang Q, Inanc B, Schamus S, Wang XH, Wei L, Brown AR, Svilar D, Sugrue KF, Goellner EM, Zeng X, Yates NA, Lan L, Vens C, Sobol RW. Fang Q, et al. Among authors: lan l. Nat Commun. 2014 Nov 26;5:5513. doi: 10.1038/ncomms6513. Nat Commun. 2014. PMID: 25423885 Free PMC article.

6

m⁵C modification of mRNA serves a DNA damage code to promote homologous recombination.

Chen H, Yang H, Zhu X, Yadav T, Ouyang J, Truesdell SS, Tan J, Wang Y, Duan M, Wei L, Zou L, Levine AS, Vasudevan S, Lan L. Chen H, et al. Among authors: lan l. Nat Commun. 2020 Jun 5;11(1):2834. doi: 10.1038/s41467-020-16722-7. Nat Commun. 2020. PMID: 32503981 Free PMC article.

7

Author Correction: Meiotic protein SYCP2 confers resistance to DNA-damaging agents through R-loop-mediated DNA repair.

Wang Y, Gao B, Zhang L, Wang X, Zhu X, Yang H, Zhang F, Zhu X, Zhou B, Yao S, Nagayama A, Lee S, Ouyang J, Koh SB, Eisenhauer EL, Zarrella D, Lu K, Rueda BR, Zou L, Su XA, Yeku O, Ellisen LW, Wang XS, Lan L. Wang Y, et al. Among authors: lan l. Nat Commun. 2024 May 7;15(1):3819. doi: 10.1038/s41467-024-48241-0. Nat Commun. 2024. PMID: 38714829 Free PMC article. No abstract available.

8

RNA transcripts stimulate homologous recombination by forming DR-loops.

Ouyang J, Yadav T, Zhang JM, Yang H, Rheinbay E, Guo H, Haber DA, Lan L, Zou L. Ouyang J, et al. Among authors: lan l. Nature. 2021 Jun;594(7862):283-288. doi: 10.1038/s41586-021-03538-8. Epub 2021 May 12. Nature. 2021. PMID: 33981036 Free PMC article.

9

RAD52 is required for RNA-templated recombination repair in post-mitotic neurons.

Welty S, Teng Y, Liang Z, Zhao W, Sanders LH, Greenamyre JT, Rubio ME, Thathiah A, Kodali R, Wetzel R, Levine AS, Lan L. Welty S, et al. Among authors: lan l. J Biol Chem. 2018 Jan 26;293(4):1353-1362. doi: 10.1074/jbc.M117.808402. Epub 2017 Dec 7. J Biol Chem. 2018. PMID: 29217771 Free PMC article.

10

DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination.

Wei L, Nakajima S, Böhm S, Bernstein KA, Shen Z, Tsang M, Levine AS, Lan L. Wei L, et al. Among authors: lan l. Proc Natl Acad Sci U S A. 2015 Jul 7;112(27):E3495-504. doi: 10.1073/pnas.1507105112. Epub 2015 Jun 22. Proc Natl Acad Sci U S A. 2015. PMID: 26100862 Free PMC article.

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