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Optimization of potent, broad-spectrum, and specific anti-influenza compounds targeting RNA polymerase PA-PB1 heterodimerization.
Bonomini A, Felicetti T, Pacetti M, Bertagnin C, Coletti A, Giammarino F, De Angelis M, Poggialini F, Macchiarulo A, Sabatini S, Mercorelli B, Nencioni L, Vicenti I, Dreassi E, Cecchetti V, Tabarrini O, Loregian A, Massari S. Bonomini A, et al. Among authors: de angelis m. Eur J Med Chem. 2024 Nov 5;277:116737. doi: 10.1016/j.ejmech.2024.116737. Epub 2024 Aug 3. Eur J Med Chem. 2024. PMID: 39153334
System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2.
Vicenti I, Martina MG, Boccuto A, De Angelis M, Giavarini G, Dragoni F, Marchi S, Trombetta CM, Crespan E, Maga G, Eydoux C, Decroly E, Montomoli E, Nencioni L, Zazzi M, Radi M. Vicenti I, et al. Among authors: de angelis m. Eur J Med Chem. 2021 Nov 15;224:113683. doi: 10.1016/j.ejmech.2021.113683. Epub 2021 Jul 5. Eur J Med Chem. 2021. PMID: 34273661 Free PMC article.
Identification of Anti-Influenza A Compounds Inhibiting the Viral Non-Structural Protein 1 (NS1) Using a Type I Interferon-Driven Screening Strategy.
Marsili G, Acchioni C, Remoli AL, Amatore D, Sgarbanti R, De Angelis M, Orsatti R, Acchioni M, Astolfi A, Iraci N, Puzelli S, Facchini M, Perrotti E, Cecchetti V, Sabatini S, Superti F, Agamennone M, Barreca ML, Hiscott J, Nencioni L, Sgarbanti M. Marsili G, et al. Among authors: de angelis m. Int J Mol Sci. 2023 Jun 22;24(13):10495. doi: 10.3390/ijms241310495. Int J Mol Sci. 2023. PMID: 37445672 Free PMC article.
Redox-Modulating Agents in the Treatment of Viral Infections.
Checconi P, De Angelis M, Marcocci ME, Fraternale A, Magnani M, Palamara AT, Nencioni L. Checconi P, et al. Among authors: de angelis m. Int J Mol Sci. 2020 Jun 8;21(11):4084. doi: 10.3390/ijms21114084. Int J Mol Sci. 2020. PMID: 32521619 Free PMC article. Review.
1,423 results