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Subtype-specific conformational landscape of NMDA receptor gating.
Bleier J, Furtado de Mendonca PR, Habrian CH, Stanley C, Vyklicky V, Isacoff EY. Bleier J, et al. Among authors: vyklicky v. Cell Rep. 2024 Aug 27;43(8):114634. doi: 10.1016/j.celrep.2024.114634. Epub 2024 Aug 17. Cell Rep. 2024. PMID: 39154344 Free PMC article.
Effects of Pregnanolone Glutamate and Its Metabolites on GABAA and NMDA Receptors and Zebrafish Behavior.
Abramova V, Leal Alvarado V, Hill M, Smejkalova T, Maly M, Vales K, Dittert I, Bozikova P, Kysilov B, Hrcka Krausova B, Vyklicky V, Balik A, Fili K, Korinek M, Chodounska H, Kudova E, Ciz D, Martinovic J, Cerny J, Bartunek P, Vyklicky L. Abramova V, et al. Among authors: vyklicky v. ACS Chem Neurosci. 2023 May 17;14(10):1870-1883. doi: 10.1021/acschemneuro.3c00131. Epub 2023 May 1. ACS Chem Neurosci. 2023. PMID: 37126803 Free PMC article.
Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations.
Kysilov B, Hrcka Krausova B, Vyklicky V, Smejkalova T, Korinek M, Horak M, Chodounska H, Kudova E, Cerny J, Vyklicky L. Kysilov B, et al. Among authors: vyklicky v. Br J Pharmacol. 2022 Aug;179(15):3970-3990. doi: 10.1111/bph.15841. Epub 2022 Apr 8. Br J Pharmacol. 2022. PMID: 35318645 Free article.
Palmitoylation Controls NMDA Receptor Function and Steroid Sensitivity.
Hubalkova P, Ladislav M, Vyklicky V, Smejkalova T, Hrcka Krausova B, Kysilov B, Krusek J, Naimová Z, Korinek M, Chodounska H, Kudova E, Cerny J, Vyklicky L Jr. Hubalkova P, et al. Among authors: vyklicky v. J Neurosci. 2021 Mar 10;41(10):2119-2134. doi: 10.1523/JNEUROSCI.2654-20.2021. Epub 2021 Feb 1. J Neurosci. 2021. PMID: 33526476 Free PMC article.
Conformational pathway provides unique sensitivity to a synaptic mGluR.
Habrian CH, Levitz J, Vyklicky V, Fu Z, Hoagland A, McCort-Tranchepain I, Acher F, Isacoff EY. Habrian CH, et al. Among authors: vyklicky v. Nat Commun. 2019 Dec 5;10(1):5572. doi: 10.1038/s41467-019-13407-8. Nat Commun. 2019. PMID: 31804469 Free PMC article.
Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor.
Donthamsetti PC, Broichhagen J, Vyklicky V, Stanley C, Fu Z, Visel M, Levitz JL, Javitch JA, Trauner D, Isacoff EY. Donthamsetti PC, et al. Among authors: vyklicky v. J Am Chem Soc. 2019 Jul 24;141(29):11522-11530. doi: 10.1021/jacs.9b02895. Epub 2019 Jul 10. J Am Chem Soc. 2019. PMID: 31291105 Free PMC article.
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